Coronary perfusion pressure

Coronary perfusion pressure

Coronary perfusion pressure (CPP) refers to the pressure gradient that drives coronary blood pressure, meaning the difference between the aortic diastolic pressure and the right atrial pressure. It is a term used mainly in research concerning cardiac arrest. In this context, it is assumed that the minimum CPP needed for a successful outcome is 15mm Hg.

Coronary Perfusion Pressure (CPP)is a part of normal blood pressure, that is specifically responsible for coronary blood flow. CPP is also, generally, a surrogate term for coronary blood flow.

During cardiac arrest, CPP is one of the most important variables in achieving Return Of Spontaneous Circulation (ROSC equals getting a pulse again after pulseless arrest). We need a minimum amount of coronary perfusion pressure to achieve ROSC. This is thought to be 15 mmhg at a minimum.

References

  • Disorders of circulatory flow. In The ICU Book. Lipincott Williams and Wilkins, 2007, p. 287

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