Ciluprevir

Ciluprevir
Ciluprevir
Systematic (IUPAC) name
(1S,4R,6S,7Z,14S,18R)-14- {[(cyclopentyloxy)carbonyl]amino}-18-[(7-methoxy-2- {2-[(propan-2-yl)amino]-1,3-thiazol-4-yl}quinolin-4- yl)oxy]-2,15-dioxo-3,16- diazatricyclo[14.3.0.0{4,6}]nonadec-7-ene-4- carboxylic acid
Clinical data
Trade names Biln-2061
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 300832-84-2
ATC code  ?
UNII 75C8DU40T0 YesY
ChEMBL CHEMBL297884
Chemical data
Formula C40H50N6O8S 
Mol. mass 774.93 g/mol

Ciluprevir is used in the treatment of hepatitis C. It is manufactured by Boehringer Ingelheim Pharma GmbH & Co. KG under the research code of BILN-2061. It is targeted against NS2-3 protease.[1]

References

  1. ^ Abbenante, G; Fairlie, DP (2005). "Protease inhibitors in the clinic". Medicinal chemistry 1 (1): 71–104. PMID 16789888.