Chymotrypsin C (caldecrin)
Symbols CTRC; CLCR; ELA4
External IDs OMIM601405 MGI1923951 HomoloGene21422 GeneCards: CTRC Gene
EC number
Species Human Mouse
Entrez 11330 76701
Ensembl ENSG00000162438 ENSMUSG00000062478
UniProt Q99895 Q3SYP2
RefSeq (mRNA) NM_007272 NM_001033875.2
RefSeq (protein) NP_009203 NP_001029047.1
Location (UCSC) Chr 1:
15.76 – 15.78 Mb
Chr 4:
141.39 – 141.4 Mb
PubMed search [1] [2]

Chymotrypsin C, also known as caldecrin or elastase 4 is an enzyme that in humans is encoded by the CTRC gene.[1][2]


Chymotrypsin C is a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity.[1]


  1. ^ a b "Entrez Gene: chymotrypsin C (caldecrin)". 
  2. ^ Tomomura A, Akiyama M, Itoh H, Yoshino I, Tomomura M, Nishii Y, Noikura T, Saheki T (May 1996). "Molecular cloning and expression of human caldecrin". FEBS Lett. 386 (1): 26–8. doi:10.1016/0014-5793(96)00377-8. PMID 8635596. 

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