- Chloroethylnorapomorphine
-
Chloroethylnorapomorphine 
6-(2-Chloro-ethyl)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolOther names(-)-N-(2-Chloroethyl)-norapomorphineIdentifiers CAS number 75946-94-0 PubChem 156376 ChemSpider 137707 
ChEMBL CHEMBL283871 Jmol-3D images Image 1 - C1CN([C@@H]2CC3=C(C4=C2C1=CC=C4)C(=C(C=C3)O)O)CCCl
- InChI=1S/C18H18ClNO2/c19-7-9-20-8-6-11-2-1-3-13-16(11)14(20)10-12-4-5-15(21)18(22)17(12)13/h1-5,14,21-22H,6-10H2/t14-/m1/s1
Key: RMKWDBUEXHJPRZ-CQSZACIVSA-N
Properties Molecular formula C18H18ClNO2 Molar mass 315.79 g/mol 
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)Infobox references Chloroethylnorapomorphine is a chemical once thought to be an irreversible dopamine D2 receptor antagonist;[1][2] however, it was later proved to be reversible.[3]
References
- ^ Cohen SA, Neumeyer JL. (Oct 1983). "Kinetics of solvolysis of N-(2-chloroethyl)norapomorphine, an irreversible dopamine receptor antagonist". Journal of Medicinal Chemistry 26 (10): 1348–53. doi:10.1021/jm00364a003. PMID 6620296.
- ^ Guan JH, Neumeyer JL, Filer CN, Ahern DG, Lilly L, Watanabe M, Grigoriadis D, Seeman P. (Jun 1984). "N-(2-chloroethyl) [8,9-2H]norapomorphine, an irreversible ligand for dopamine receptors: synthesis and application". Journal of Medicinal Chemistry 27 (6): 806–10. doi:10.1021/jm00372a019. PMID 6737423.
- ^ Lehmann, J; Langer, SZ (1982). "Dopamine autoreceptors differ pharmacologically from postsynaptic dopamine receptors: Effects of (−)-N-(2-chloroethyl)-norapomorphine". European Journal of Pharmacology 77 (1): 85. doi:10.1016/0014-2999(82)90542-8. PMID 7060630.
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