Hydrangenol

Hydrangenol
Hydrangenol
Chemical structure of hydrangenol
IUPAC name
8-hydroxy-3-(4-hydroxyphenyl)-3,4-dihydroisochromen-1-one
Identifiers
CAS number 480-47-7
PubChem 119199
Jmol-3D images Image 1
Properties
Molecular formula C15H12O4
Molar mass 256.25 g/mol
Exact mass 256.073559 u
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Hydrangenol is an dihydroisocoumarin. It can found in Hydrangea macrophylla, as well as its 8-O-glucoside.[1] (-)-hydrangenol 4'-O-glucoside[2] and (+)-hydrangenol 4'-O-glucoside[3]can be found in Hydrangeae Dulcis Folium, the processed leaves of H. macrophylla var. thunbergii.

References

  1. ^ Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and Thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Matsuda H., Shimoda H., Yamahara J. and Yoshikawa M., Biological & pharmaceutical bulletin, 1999, vol. 22, no8, pp. 870-872, INIST:1959604
  2. ^ Thunberginols C, D, and E, new antiallergic and antimicrobial dihydroisocoumarins, and thunberginol G 3'-O-glucoside and (-)-hydrangenol 4'-O-glucoside, new dihydroisocoumarin glycosides, from Hydrangeae Dulcis Folium. Yoshikawa M, Uchida E, Chatani N, Kobayashi H, Naitoh Y, Okuno Y, Matsuda H, Yamahara J and Murakami N. Chem Pharm Bull (Tokyo). 1992 Dec;40(12), pp. 3352-3354, PubMed
  3. ^ Development of bioactive functions in hydrangeae dulcis folium. V. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (2). Thunberginols C, D, and E, thunberginol G 3'-O-glucoside, (-)-hydrangenol 4'-o-glucoside, and (+)-hydrangenol 4'-O-glucoside. Yoshikawa M, Matsuda H, Shimoda H, Shimada H, Harada E, Naitoh Y, Miki A, Yamahara J and Murakami N, Chem Pharm Bull (Tokyo). 1996 Aug;44(8), pp. 1440-1447, PubMed, INIST:3226693
v · isocoumarins
Aglycones
Bergenon | Thunberginol A and B
Dihydroisocoumarins
Hydrangenol | Phyllodulcin | Thunberginol C, D, E and G
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