Gamma-150 RNA motif

The gamma-150 RNA motif is a conserved RNA structure that is found in bacteria within the order Pseudomonadales. [cite journal |author=Weinberg Z, Barrick JE, Yao Z, "et al" |title=Identification of 22 candidate structured RNAs in bacteria using the CMfinder comparative genomics pipeline |journal=Nucleic Acids Res. |volume=35 |issue=14 |pages=4809–19 |year=2007 |pmid=17621584 |pmc=1950547 |doi=10.1093/nar/gkm487 |url=] Because gamma-150 RNAs are not consistently in 5' UTRs, the gamma-150 motif is presumed to correspond to a non-coding RNA.

Structurally, the gamma-150 motif consists of four independent stem-loops. The first stem-loop (the stem-loop closest to the 5' end of the RNA) has significant covariation in support of its identity as an RNA (see secondary structure prediction). The second and fourth have more modest evidence, while the third stem-loop might be poorly conserved, or not genuine. Several regions of high conservation of nucleotide identity are present throughout the RNA motif, and many contain short runs of adenosines.

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