Fink Effect

Fink Effect

The Fink effect, or "third gas effect" is a factor that influences the PO2 of alveolar gas. When soluble gases are breathed in (eg. NO2) large quantities can be dissolved in body fluids rapidly. This can lead to a temporary increase in the concentration of oxygen and carbon dioxide in the alveolus, causing an increase in their respective partial pressures.

When a patient is recovering from NO2 anaesthesia, large quantities of this gas cross from the blood into the alveolus (down it's concentration gradient) and so for a short period of time, the O2 and CO2 in the alveolus are diluted by this gas. This could potentially cause the partial pressure of oxygen to decrease and could temporarily lead to hypoxia. The decrease in CO2 could also potentiate this effect as ventilation would be suppressed, leading to potential hypoxaemia. Nonetheless, this effect would only last a couple of minutes and hypoxia can be avoided by increasing the fractional inspired oxygen concentration when recovering from NO2 anaesthesia. [Nunn Respiratory Physiology p169]

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Fink effect — The Fink effect, also known as diffusion anoxia ,[1] diffusion hypoxia ,[2] or the third gas effect ,[3] is a factor that influences the Po2 (partial pressure of oxygen) within the alveolus. When soluble gases are breathed in (e.g. nitrous oxide …   Wikipedia

  • Concentration effect — During induction of general anesthesia when a large volume of nitrous oxide is taken up from alveoli into pulmonary capillary blood, the concentration of gases remaining in the alveoli is altered. This results in effects known as the… …   Wikipedia

  • Max Fink — (born 1923) is an American psychiatrist best known for his work on ECT (electroconvulsive therapy). Contents 1 Early life, marriage and qualifications 2 Academic positions, research and awards 3 Retirement …   Wikipedia

  • Epidural — This article is about the anaesthetic technique. For the anatomical site, see Epidural space. For other uses, see Epidural (disambiguation). Did you mean Epidural hematoma, a type of traumatic brain injury? Epidural Intervention …   Wikipedia

  • Midazolam — Systematic (IUPAC) name 8 chloro 6 (2 fluorophenyl) 1 methyl 4H imidazo[1,5 …   Wikipedia

  • Hypoxia (medical) — Hypoxia ICD 9 799.02 MeSH D000860 Hypoxia, or hypoxiation, is a pathological condition in which the body as a whole (generalized hypoxia) or a region of the body (tissue hypoxia) is deprived of adequate ox …   Wikipedia

  • Minimum alveolar concentration — or MAC is a concept used to compare the strengths, or potency, of anaesthetic vapours;[1] in simple terms, it is defined as the concentration of the vapour in the lungs that is needed to prevent movement (motor response) in 50% of subjects in… …   Wikipedia

  • Anesthesia — Not to be confused with Paresthesia. For other uses, see Anesthesia (disambiguation). Anesthesia, or anaesthesia (see spelling differences; from Greek αν , an , without ; and αἴσθησις, aisthēsis, sensation ), traditionally meant the condition of… …   Wikipedia

  • Oral sedation dentistry — is a medical procedure involving the administration of oral sedative drugs, generally to facilitate a dental procedure and reduce patients fear and anxiety related to the experience. Oral sedation is one of the available methods of conscious… …   Wikipedia

  • Local anesthesia — Intervention MeSH D000772 Local anesthesia is any technique to induce the absence of sensation in part of the body,[1] generally fo …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”