DOCK (protein)

"Zir" redirects here. For other uses, see Zir (disambiguation)

Dedicator of cytokinesis
Identifiers
Symbol	Ded_cyto
Pfam	PF06920
InterPro	IPR010703
SCOP	1wg7
Available protein structures: Pfam structures PDB RCSB PDB; PDBe PDBsum structure summary

DOCK (Dedicator of cytokinesis) is a family of related proteins involved in intracellular signalling networks.^[1] Studies to date suggest that this family act as guanine nucleotide exchange factors for small G proteins of the Rho family, such as Rac and Cdc42. DOCK family proteins are categorised into four subfamilies based on their sequence homology:

• DOCK-A subfamily
  • Dock180 (also known as Dock1)
  • Dock2
  • Dock5
• DOCK-B subfamily
  • Dock3 (also known as MOCA and PBP)
  • Dock4
• DOCK-C subfamily (also known as Zir subfamily)
  • Dock6 (also known as Zir1)
  • Dock7 (also known as Zir2)
  • Dock8 (also known as Zir3)
• DOCK-D subfamily (also known as Zizimin subfamily)
  • Dock9 (also known as Zizimin1)
  • Dock10 (also known as Zizimin3)
  • Dock11 (also known as Zizimin2)

References

1. ^ Côté JF, Vuori K (December 2002). "Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity". J. Cell. Sci. 115 (Pt 24): 4901–13. doi:10.1242/jcs.00219. PMID 12432077. 

This protein-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Protein stubs GTP-binding protein regulators Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? Maharaja Ranjit Singh's throne Luisa Piccarreta Look at other dictionaries: Dock — Contents 1 In transportation 2 In natural sciences 3 In molecular biology …   Wikipedia DOCK — The program UCSF DOCK was created in the 1980s by Irwin Tack Kuntz s Group, and was the first docking program.[1] DOCK uses geometric algorithms to predict the binding modes of small molecules.[2][3][4] Brian K. Shoichet, David A. Case, and… …   Wikipedia Omega Protein — Corporation Type Public (NYSE: OME) Industry Fish products Founded 1998 …   Wikipedia Antifreeze protein — Antifreeze proteins (AFPs) or ice structuring proteins (ISPs) refer to a class of polypeptides produced by certain vertebrates, plants, fungi and bacteria that permit their survival in subzero environments. AFPs bind to small ice crystals to… …   Wikipedia Curled Dock — Taxobox color = lightgreen name = Rumex crispus status = secure image width = 240px regnum = Plantae divisio = Magnoliophyta classis = Magnoliopsida ordo = Caryophyllales familia = Polygonaceae genus = Rumex species = R. crispus binomial = Rumex… …   Wikipedia Dock2 — Dedicator of cytokinesis 2 Rendering based on PDB 2RQR …   Wikipedia Dock7 — Dedicator of cytokinesis 7 Identifiers Symbols DOCK7; KIAA1771; ZIR2 External IDs …   Wikipedia Dock4 — Dedicator of cytokinesis 4 Identifiers Symbols DOCK4; FLJ34238; KIAA0716; MGC134911; MGC134912 External IDs …   Wikipedia Dock9 — Dedicator of cytokinesis 9 PDB rendering based on 1wg7 …   Wikipedia Dock3 — Dedicator of cytokinesis 3 Identifiers Symbols DOCK3; KIAA0299; MOCA; PBP External IDs …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”