Pyrrolidinylthiambutene

Pyrrolidinylthiambutene

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IUPAC_name = 1-(4,4-di(thiophen-2-yl)but-3-en-2-yl)pyrrolidine


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C=16 | H=19 | N=1 | S=2
molecular_weight = 289.458 g/mol
smiles = C2CCCN2C(C)C=C(c1sccc1)c3sccc3
melting_point = 167
melting_high = 169
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Pyrrolidinylthiambutene is an opioid analgesic drug from the thiambutene family with around 3/4 of the potency of morphine. [Adamson DW, Green AF. A new series of analgesics. "Nature". 1950 Jan 21;165(4186):122. PMID 15409854] [Adamson DW, Duffin WM, Green AF. Dithienylbutylamines as analgesics. "Nature". 1951 Jan 27;167(4239):153-4. PMID 14806409] [Green AF. Analgesic and other properties of 3: 3-dithienylalkenylamines. "British Journal of Pharmacology and Chemotherapy". 1953 Mar;8(1):2-9. PMID 13066683] It would be considered an illegal controlled substance analogue in some countries such as the USA, Australia and New Zealand, but is legal in countries not possessing a controlled-substances-analog-act equivalent.

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