- Diabetes and Cognition
Type II diabetes mellitus (DM2) has been associated with an increased risk of cognitive dysfunction and dementia through disease processes such as Alzheimer's disease and vascular dementia. Researchers have shown that reduced glucose tolerance has deleterious effects on memory in the elderly, and concomitant hippocampal atrophy. [Convit A, Wolf OT, Tarshish C, de Leon MJ. Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderly. Proc Natl Acad Sci U S A. Feb 18 2003;100(4):2019-2022.]
Pathophysiology Diabetes' Neurological Sequelae
There is growing evidence that the increased risk for cognitive dysfunction associated with Diabetes is related through a variety of pathways.
References
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