Diazaborine

Diazaborine: Diazaborine

IUPAC name

2-[(4-Methylphenyl)sulfonyl]-2,3,1-benzodiazaborinin-1(2H)-ol

Identifiers

CAS number 22959-81-5^Y

PubChem 481709

ChemSpider 422598

Jmol-3D images Image 1

SMILES

O=S(=O)(N2/N=C\c1c(cccc1)B2O)c3ccc(cc3)C

InChI

InChI=InChI=1S/C14H13BN2O3S/c1-11-6-8-13(9-7-11)21(19,20)17-15(18)14-5-3-2-4-12(14)10-16-17/h2-10,18H,1H3

Properties

Molecular formula C₁₄H₁₃BN₂O₃S

Molar mass 300.14 g mol⁻¹

Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)

Infobox references

Diazaborine is a drug that inhibits maturation of rRNAs for the large ribosomal subunit. This may have implications for anti-aging therapies in future.^[1]

References

^ Pertschy, B.; Zisser, G.; Schein, H.; Koffel, R.; Rauch, G.; Grillitsch, K.; Morgenstern, C.; Durchschlag, M. et al. (2004). "Diazaborine Treatment of Yeast Cells Inhibits Maturation of the 60S Ribosomal Subunit". Molecular and Cellular Biology 24 (14): 6476–6487. doi:10.1128/MCB.24.14.6476-6487.2004. PMC 434233. PMID 15226447. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=434233.

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Academic Dictionaries and Encyclopedias

Diazaborine

IUPAC name 2-[(4-Methylphenyl)sulfonyl]-2,3,1-benzodiazaborinin-1(2H)-ol
Identifiers
CAS number	22959-81-5^Y
PubChem	481709
ChemSpider	422598
Jmol-3D images	Image 1
SMILES O=S(=O)(N2/N=C\c1c(cccc1)B2O)c3ccc(cc3)C
InChI InChI=InChI=1S/C14H13BN2O3S/c1-11-6-8-13(9-7-11)21(19,20)17-15(18)14-5-3-2-4-12(14)10-16-17/h2-10,18H,1H3
Properties
Molecular formula	C₁₄H₁₃BN₂O₃S
Molar mass	300.14 g mol⁻¹
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references