DCBLD2

Discoidin, CUB and LCCL domain containing 2
Identifiers
Symbols	DCBLD2; CLCP1; ESDN
External IDs	OMIM: 608698 MGI: 1920629 HomoloGene: 12499 GeneCards: DCBLD2 Gene
Gene Ontology Molecular function • protein binding Cellular component • integral to plasma membrane • cell surface • membrane Biological process • cell adhesion • negative regulation of cell growth • intracellular receptor mediated signaling pathway • wound healing Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	131566	73379
Ensembl	ENSG00000057019	ENSMUSG00000035107
UniProt	Q96PD2	Q91ZH3
RefSeq (mRNA)	NM_080927.3	NM_028523.3
RefSeq (protein)	NP_563615.3	NP_082799.2
Location (UCSC)	Chr 3: 98.51 – 98.62 Mb	Chr 16: 58.41 – 58.47 Mb
PubMed search	[1]	[2]

Discoidin, CUB and LCCL domain-containing protein 2 is a protein that in humans is encoded by the DCBLD2 gene.^[1][2]

References

1. ^ Kobuke K, Furukawa Y, Sugai M, Tanigaki K, Ohashi N, Matsumori A, Sasayama S, Honjo T, Tashiro K (Sep 2001). "ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury". J Biol Chem 276 (36): 34105–14. doi:10.1074/jbc.M105293200. PMID 11447234. 
2. ^ "Entrez Gene: DCBLD2 discoidin, CUB and LCCL domain containing 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=131566. 

Further reading

• Sadeghi MM, Esmailzadeh L, Zhang J, et al. (2007). "ESDN is a marker of vascular remodeling and regulator of cell proliferation in graft arteriosclerosis.". Am. J. Transplant. 7 (9): 2098–105. doi:10.1111/j.1600-6143.2007.01919.x. PMID 17697260. 
• Chen Y, Low TY, Choong LY, et al. (2007). "Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells.". Proteomics 7 (14): 2384–97. doi:10.1002/pmic.200600968. PMID 17570516. 
• Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.". Mol. Cell Proteomics 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Koshikawa K, Osada H, Kozaki K, et al. (2002). "Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo.". Oncogene 21 (18): 2822–8. doi:10.1038/sj.onc.1205405. PMID 11973641. 
• Nadadur SS, Ehrke MJ, Gurtoo HL (2000). "A novel TNF-inducible message with putative growth suppressor function.". Biochim. Biophys. Acta 1489 (2–3): 433–9. PMID 10673047.