CPA5

Carboxypeptidase A5, also known as CPA5, is a human gene.cite web | title = Entrez Gene: CPA5 carboxypeptidase A5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=93979| accessdate = ]

PBB_Summary
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summary_text = Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002). [supplied by OMIM] cite web | title = Entrez Gene: CPA5 carboxypeptidase A5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=93979| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Bentley L, Nakabayashi K, Monk D, "et al." |title=The imprinted region on human chromosome 7q32 extends to the carboxypeptidase A gene cluster: an imprinted candidate for Silver-Russell syndrome. |journal=J. Med. Genet. |volume=40 |issue= 4 |pages= 249-56 |year= 2003 |pmid= 12676894 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bonora E, Bacchelli E, Levy ER, "et al." |title=Mutation screening and imprinting analysis of four candidate genes for autism in the 7q32 region. |journal=Mol. Psychiatry |volume=7 |issue= 3 |pages= 289-301 |year= 2002 |pmid= 11920156 |doi= 10.1038/sj.mp.4001004
*cite journal | author=Wei S, Segura S, Vendrell J, "et al." |title=Identification and characterization of three members of the human metallocarboxypeptidase gene family. |journal=J. Biol. Chem. |volume=277 |issue= 17 |pages= 14954-64 |year= 2002 |pmid= 11836249 |doi= 10.1074/jbc.M112254200
*cite journal | author= |title=A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of Autism Consortium. |journal=Hum. Mol. Genet. |volume=7 |issue= 3 |pages= 571-8 |year= 1998 |pmid= 9546821 |doi=

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