P53AIP1

Tumor protein p53 regulated apoptosis inducing protein 1
Identifiers
Symbols	TP53AIP1;
External IDs	OMIM: 605426 GeneCards: TP53AIP1 Gene
Gene Ontology Molecular function • molecular_function Cellular component • mitochondrion Biological process • apoptosis Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	63970	n/a
Ensembl	ENSG00000120471	n/a
UniProt	Q9HCN2	n/a
RefSeq (mRNA)	NM_001195194.1	n/a
RefSeq (protein)	NP_001182123.1	n/a
Location (UCSC)	Chr 11: 128.8 – 128.81 Mb	n/a
PubMed search	[1]	n/a

p53-regulated apoptosis-inducing protein 1 is a protein that in humans is encoded by the TP53AIP1 gene.^[1][2][3]

References

1. ^ Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y, Taya Y (Oct 2000). "p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53". Cell 102 (6): 849–62. doi:10.1016/S0092-8674(00)00073-8. PMID 11030628. 
2. ^ Matsuda K, Yoshida K, Taya Y, Nakamura K, Nakamura Y, Arakawa H (May 2002). "p53AIP1 regulates the mitochondrial apoptotic pathway". Cancer Res 62 (10): 2883–9. PMID 12019168. 
3. ^ "Entrez Gene: P53AIP1 p53-regulated apoptosis-inducing protein 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63970. 

Further reading

• Strano S, Monti O, Pediconi N, et al. (2005). "The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.". Mol. Cell 18 (4): 447–59. doi:10.1016/j.molcel.2005.04.008. PMID 15893728. 
• Wesierska-Gadek J, Gueorguieva M, Horky M (2005). "Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells.". Mol. Cancer Ther. 4 (1): 113–24. PMID 15657359. 
• Chan KT, Lung ML (2004). "Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line.". Cancer Chemother. Pharmacol. 53 (6): 519–26. doi:10.1007/s00280-004-0767-4. PMID 15004724. 
• Kövesi G, Szende B (2004). "Changes in apoptosis and mitotic index, p53 and Ki67 expression in various types of oral leukoplakia.". Oncology 65 (4): 331–6. doi:10.1159/000074646. PMID 14707453. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome.". Science 291 (5507): 1304–51. doi:10.1126/science.1058040. PMID 11181995.