Angiomotin

Angiomotin

Angiomotin is a 675-residue protein that increases the random migration of endothelial cells as well as the migration of endothelial cells toward growth factors.

In the presence of angiostatin, endothelial cells that overexpress angiomotin exhibit a significant reduction in migration toward growth factors as well as an inability to form tubules in vitro. These observations are consistent with the localization of angiomotin in the leading edge of migrating cells. Angiostatin, therefore, disrupts the normal migratory function of Angiomotin.


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  • AMOT — Angiomotin, also known as AMOT, is a human gene.cite web | title = Entrez Gene: AMOT angiomotin| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=154796| accessdate = ] PBB Summary section title = summary… …   Wikipedia

  • AMOTL2 — Angiomotin like 2, also known as AMOTL2, is a human gene.cite web | title = Entrez Gene: AMOTL2 angiomotin like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=51421| accessdate = ] PBB Summary section… …   Wikipedia

  • AMOTL1 — Angiomotin like 1, also known as AMOTL1, is a human gene.cite web | title = Entrez Gene: AMOTL1 angiomotin like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=154810| accessdate = ] PBB Summary section… …   Wikipedia

  • Angiostatin — is a naturally occurring protein found in several animal species, including humans. It is an endogenous angiogenesis inhibitor (i.e., it blocks the growth of new blood vessels), and it is currently undergoing clinical trials for its use in… …   Wikipedia

  • MAGI1 — Membrane associated guanylate kinase, WW and PDZ domain containing 1, also known as MAGI1, is a human gene.cite web | title = Entrez Gene: MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1| url =… …   Wikipedia

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