- IL2RA
Interleukin 2 receptor, alpha, also known as IL2RA, is a human
gene .PBB_Summary
section_title =
summary_text = The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. [cite web | title = Entrez Gene: IL2RA interleukin 2 receptor, alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3559| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal |author=Kuziel WA, Greene WC |title=Interleukin-2 and the IL-2 receptor: new insights into structure and function |journal=J. Invest. Dermatol. |volume=94 |issue=6 Suppl |pages=27S–32S |year=1990 |month=June |pmid=1693645 |doi= 10.1111/1523-1747.ep12875017|url= |accessdate=2008-08-04
*cite journal |author=Waldmann TA |title=The interleukin-2 receptor |journal=J. Biol. Chem. |volume=266 |issue=5 |pages=2681–4 |year=1991 |month=February |pmid=1993646 |doi= |url=http://www.jbc.org/cgi/pmidlookup?view=long&pmid=1993646 |accessdate=2008-08-04
*cite journal |author=Murakami S |title=Soluble interleukin-2 receptor in cancer |journal=Front. Biosci. |volume=9 |issue= |pages=3085–90 |year=2004 |month=September |pmid=15353339 |doi= 10.2741/1461|url=http://www.bioscience.org/2004/v9/af/1461/fulltext.htm |accessdate=2008-08-04
*cite journal |author=Vincenti F |title=Interleukin-2 receptor antagonists and aggressive steroid minimization strategies for kidney transplant patients |journal=Transpl. Int. |volume=17 |issue=8 |pages=395–401 |year=2004 |month=September |pmid=15365604 |doi=10.1007/s00147-004-0750-3 |url=http://www.blackwell-synergy.com/openurl?genre=article&sid=nlm:pubmed&issn=0934-0874&date=2004&volume=17&issue=8&spage=395 |accessdate=2008-08-04PBB_Controls
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