ZMPSTE24

protein
Name=zinc metallopeptidase (STE24 homolog, S. cerevisiae)
caption=


width=
HGNCid=12877
Symbol=ZMPSTE24
AltSymbols=
EntrezGene= 10269
OMIM=606480
RefSeq= NM_005857
UniProt= O75844
PDB=
ECnumber=3.4.24.84
Chromosome=1
Arm=p
Band=34
LocusSupplementaryData=

ZMPSTE24 is a human gene.cite journal | author = Tam A, Nouvet FJ, Fujimura-Kamada K, Slunt H, Sisodia SS, Michaelis S | title = Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing | journal = J. Cell Biol. | volume = 142 | issue = 3 | pages = 635–49 | year = 1998 | month = August | pmid = 9700155 | pmc = 2148179 | doi = | url = http://www.jcb.org/cgi/pmidlookup?view=long&pmid=9700155 | issn = ] cite journal | author = Freije JM, Blay P, Pendás AM, Cadiñanos J, Crespo P, López-Otín C | title = Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins | journal = Genomics | volume = 58 | issue = 3 | pages = 270–80 | year = 1999 | month = June | pmid = 10373325 | doi = 10.1006/geno.1999.5834 | url = | issn = ] The protein encoded by this gene is a metallopeptidase. It is involved in the processing of Lamin A.cite journal | author = Young SG, Fong LG, Michaelis S | title = Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis | journal = J. Lipid Res. | volume = 46 | issue = 12 | pages = 2531–58 | year = 2005 | month = December | pmid = 16207929 | doi = 10.1194/jlr.R500011-JLR200 | url = | issn = ]

ee also

* progeria

References