CD79A

CD79a molecule, immunoglobulin-associated alpha, also known as CD79A (Cluster of Differentiation 79A), is a human gene.cite web | title = Entrez Gene: CD79A CD79a molecule, immunoglobulin-associated alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=973| accessdate = ]

PBB_Summary
section_title =
summary_text = The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.cite web | title = Entrez Gene: CD79A CD79a molecule, immunoglobulin-associated alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=973| accessdate = ]

ee also

* Cluster of differentiation

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Reth M |title=Antigen receptors on B lymphocytes. |journal=Annu. Rev. Immunol. |volume=10 |issue= |pages= 97–121 |year= 1992 |pmid= 1591006 |doi= 10.1146/annurev.iy.10.040192.000525
*cite journal | author=Herren B, Burrows PD |title=B cell-restricted human mb-1 gene: expression, function, and lineage infidelity. |journal=Immunol. Res. |volume=26 |issue= 1-3 |pages= 35–43 |year= 2003 |pmid= 12403343 |doi=
*cite journal | author=Bastian A, Kratzin H, Eckart K, Hilschmann N |title=Intra- and interchain disulfide bridges of the human J chain in secretory immunoglobulin A. |journal=Biol. Chem. Hoppe-Seyler |volume=373 |issue= 12 |pages= 1255–63 |year= 1993 |pmid= 1292512 |doi=
*cite journal | author=Leduc I, Preud'homme JL, Cogné M |title=Structure and expression of the mb-1 transcript in human lymphoid cells. |journal=Clin. Exp. Immunol. |volume=90 |issue= 1 |pages= 141–6 |year= 1992 |pmid= 1395095 |doi=
*cite journal | author=Kristensen T, Lopez R, Prydz H |title=An estimate of the sequencing error frequency in the DNA sequence databases. |journal=DNA Seq. |volume=2 |issue= 6 |pages= 343–6 |year= 1992 |pmid= 1446073 |doi=
*cite journal | author=Müller B, Cooper L, Terhorst C |title=Cloning and sequencing of the cDNA encoding the human homologue of the murine immunoglobulin-associated protein B29. |journal=Eur. J. Immunol. |volume=22 |issue= 6 |pages= 1621–5 |year= 1992 |pmid= 1534761 |doi=
*cite journal | author=Ha HJ, Kubagawa H, Burrows PD |title=Molecular cloning and expression pattern of a human gene homologous to the murine mb-1 gene. |journal=J. Immunol. |volume=148 |issue= 5 |pages= 1526–31 |year= 1992 |pmid= 1538135 |doi=
*cite journal | author=Hutchcroft JE, Harrison ML, Geahlen RL |title=Association of the 72-kDa protein-tyrosine kinase PTK72 with the B cell antigen receptor. |journal=J. Biol. Chem. |volume=267 |issue= 12 |pages= 8613–9 |year= 1992 |pmid= 1569106 |doi=
*cite journal | author=Flaswinkel H, Reth M |title=Molecular cloning of the Ig-alpha subunit of the human B-cell antigen receptor complex. |journal=Immunogenetics |volume=36 |issue= 4 |pages= 266–9 |year= 1992 |pmid= 1639443 |doi=
*cite journal | author=Yu LM, Chang TW |title=Human mb-1 gene: complete cDNA sequence and its expression in B cells bearing membrane Ig of various isotypes. |journal=J. Immunol. |volume=148 |issue= 2 |pages= 633–7 |year= 1992 |pmid= 1729378 |doi=
*cite journal | author=Venkitaraman AR, Williams GT, Dariavach P, Neuberger MS |title=The B-cell antigen receptor of the five immunoglobulin classes. |journal=Nature |volume=352 |issue= 6338 |pages= 777–81 |year= 1991 |pmid= 1881434 |doi= 10.1038/352777a0
*cite journal | author=Bakos MA, Kurosky A, Goldblum RM |title=Characterization of a critical binding site for human polymeric Ig on secretory component. |journal=J. Immunol. |volume=147 |issue= 10 |pages= 3419–26 |year= 1991 |pmid= 1940346 |doi=
*cite journal | author=Sakaguchi N, Kashiwamura S, Kimoto M, "et al." |title=B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties. |journal=EMBO J. |volume=7 |issue= 11 |pages= 3457–64 |year= 1989 |pmid= 2463161 |doi=
*cite journal | author=Grubb AO, López C, Tejler L, Mendez E |title=Isolation of human complex-forming glycoprotein, heterogeneous in charge (protein HC), and its IgA complex from plasma. Physiochemical and immunochemical properties, normal plasma concentration. |journal=J. Biol. Chem. |volume=258 |issue= 23 |pages= 14698–707 |year= 1984 |pmid= 6196366 |doi=
*cite journal | author=Kurosaki T, Johnson SA, Pao L, "et al." |title=Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling. |journal=J. Exp. Med. |volume=182 |issue= 6 |pages= 1815–23 |year= 1996 |pmid= 7500027 |doi=
*cite journal | author=Lankester AC, van Schijndel GM, Cordell JL, "et al." |title=CD5 is associated with the human B cell antigen receptor complex. |journal=Eur. J. Immunol. |volume=24 |issue= 4 |pages= 812–6 |year= 1994 |pmid= 7512031 |doi=
*cite journal | author=Vasile S, Coligan JE, Yoshida M, Seon BK |title=Isolation and chemical characterization of the human B29 and mb-1 proteins of the B cell antigen receptor complex. |journal=Mol. Immunol. |volume=31 |issue= 6 |pages= 419–27 |year= 1994 |pmid= 7514267 |doi=
*cite journal | author=Brown VK, Ogle EW, Burkhardt AL, "et al." |title=Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45. |journal=J. Biol. Chem. |volume=269 |issue= 25 |pages= 17238–44 |year= 1994 |pmid= 7516335 |doi=
*cite journal | author=Pani G, Kozlowski M, Cambier JC, "et al." |title=Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling. |journal=J. Exp. Med. |volume=181 |issue= 6 |pages= 2077–84 |year= 1995 |pmid= 7539038 |doi=

External links

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