DNER

Delta/notch-like EGF repeat containing
Identifiers
Symbols	DNER; UNQ26; bet
External IDs	OMIM: 607299 MGI: 2152889 HomoloGene: 26722 GeneCards: DNER Gene
Gene Ontology Molecular function • transmembrane receptor activity • Notch binding • calcium ion binding • protein binding • clathrin binding Cellular component • early endosome • plasma membrane • integral to membrane • dendrite • neuronal cell body Biological process • neuron migration • endocytosis • Notch signaling pathway • Notch receptor processing • synapse assembly • central nervous system development • glial cell differentiation • skeletal muscle fiber development Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	92737	227325
Ensembl	ENSG00000187957	ENSMUSG00000036766
UniProt	Q8NFT8	Q8JZM4
RefSeq (mRNA)	NM_139072	NM_152915.1
RefSeq (protein)	NP_620711	NP_690879.1
Location (UCSC)	Chr 2: 230.22 – 230.58 Mb	Chr 1: 84.37 – 84.69 Mb
PubMed search	[1]	[2]

Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene.^[1][2][3]

References

1. ^ Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M (Jul 2002). "Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons". J Biol Chem 277 (28): 25400–7. doi:10.1074/jbc.M110793200. PMID 11950833. 
2. ^ Nishizumi H, Komiyama T, Miyabayashi T, Sakano S, Sakano H (May 2002). "BET, a novel neuronal transmembrane protein with multiple EGF-like motifs". Neuroreport 13 (6): 909–15. doi:10.1097/00001756-200205070-00035. PMID 11997712. 
3. ^ "Entrez Gene: DNER delta/notch-like EGF repeat containing". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=92737. 

Further reading

• "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=403697. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621. 
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129. 
• Ramachandran P, Boontheung P, Xie Y, et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.