- Benzonatate
drugbox
IUPAC_name = 2- [2- [2- [2- [2- [2- [2- [2- (2-methoxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethyl4-butylaminobenzoate
width = 250px
CAS_number = 104-31-4
ATC_prefix = R05
ATC_suffix = DB01
ATC_supplemental =
PubChem = 7699
DrugBank = APRD00629
C=30 | H=53 | N=1 | O=11
molecular_weight = 603.742 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life = 3-8 hours
pregnancy_US = C
pregnancy_category =
legal_status =
routes_of_administration =Benzonatate or 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl "para"-butylaminobenzoate is a non-
narcotic oralantitussive (cough suppressant) last for approximately 3 hours.http://www.medicinenet.com/benzonatate/article.htm Benzonatate, from MedicineNet.com] It is sold under the brand name Tessalon Perles (gelcaps) or Tessalon Capsules.The medication must be swallowed whole. If the capsules are bitten into or sucked on, it may make the mouth numb and in some cases cause choking. [http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682640.html "Benzonatate", from Medline Plus]
It is chemically related to other
ester anesthetics such asprocaine . Benzonatate is unrelated tocodeine and other narcotics that are frequently used to suppress coughs. (Another frequently used cough suppressant,dextromethorphan , which is found in many over-the-counter cough and cold preparations, is a derivative of the narcotics.) Benzonatate was approved by the FDA in 1958.References
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