Benzonatate

Benzonatate

drugbox
IUPAC_name = 2- [2- [2- [2- [2- [2- [2- [2- (2-methoxyethoxy) ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethoxy] ethyl4-butylaminobenzoate



width = 250px
CAS_number = 104-31-4
ATC_prefix = R05
ATC_suffix = DB01
ATC_supplemental =
PubChem = 7699
DrugBank = APRD00629
C=30 | H=53 | N=1 | O=11
molecular_weight = 603.742 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life = 3-8 hours
pregnancy_US = C
pregnancy_category =
legal_status =
routes_of_administration =

Benzonatate or 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-yl "para"-butylaminobenzoate is a non-narcotic oral antitussive (cough suppressant) last for approximately 3 hours.http://www.medicinenet.com/benzonatate/article.htm Benzonatate, from MedicineNet.com] It is sold under the brand name Tessalon Perles (gelcaps) or Tessalon Capsules.

The medication must be swallowed whole. If the capsules are bitten into or sucked on, it may make the mouth numb and in some cases cause choking. [http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682640.html "Benzonatate", from Medline Plus]

It is chemically related to other ester anesthetics such as procaine. Benzonatate is unrelated to codeine and other narcotics that are frequently used to suppress coughs. (Another frequently used cough suppressant, dextromethorphan, which is found in many over-the-counter cough and cold preparations, is a derivative of the narcotics.) Benzonatate was approved by the FDA in 1958.

References


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Look at other dictionaries:

  • benzonatate — /ben zon euh tayt /, n. Pharm. a nonnarcotic substance, C30H53NO11, used as a cough suppressant. [perh. BENZO(IC ACID) + (no)na(ethylene) + t ( < ?) + ATE3] * * * …   Universalium

  • benzonatate — noun bɛnˈzownətejt A particular kind of non narcotic cough suppressant, taken orally …   Wiktionary

  • benzonatate — An antitussive agent related chemically to tetracaine; thought to act by depressing mechanoreceptors in the lungs. * * * ben·zo·na·tate (ben zoґnə tāt) [USP] a peripherally acting antitussive that reduces the cough reflex by… …   Medical dictionary

  • benzonatate — /ben zon euh tayt /, n. Pharm. a nonnarcotic substance, C30H53NO11, used as a cough suppressant. [perh. BENZO(IC ACID) + (no)na(ethylene) + t ( < ?) + ATE3] …   Useful english dictionary

  • Cough medicine — Cough syrup redirects here. For the Young the Giant song, see Cough Syrup (song). Cough medicine often contains cough suppressants or expectorants. A cough medicine (or linctus, when in syrup form) is a medicinal drug used in an attempt to treat… …   Wikipedia

  • ATC code R05 — ATC codes R Respiratory system R01 Nasal preparations R02 Throat preparations R03 Drugs for obstructive airway diseases R05 Cough and cold preparations R06 Antihistamines for systemic use …   Wikipedia

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