- KCNH5
Potassium voltage-gated channel, subfamily H (eag-related), member 5, also known as KCNH5, is a human
gene .cite web | title = Entrez Gene: KCNH5 potassium voltage-gated channel, subfamily H (eag-related), member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27133| accessdate = ]PBB_Summary
section_title =
summary_text = Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. This gene is not expressed in differentiating myoblasts. Alternative splicing results in three transcript variants encoding distinct isoforms.cite web | title = Entrez Gene: KCNH5 potassium voltage-gated channel, subfamily H (eag-related), member 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27133| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Gutman GA, Chandy KG, Grissmer S, "et al." |title=International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 473–508 |year= 2006 |pmid= 16382104 |doi= 10.1124/pr.57.4.10
*cite journal | author=Occhiodoro T, Bernheim L, Liu JH, "et al." |title=Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion. |journal=FEBS Lett. |volume=434 |issue= 1-2 |pages= 177–82 |year= 1998 |pmid= 9738473 |doi=
*cite journal | author=Volorio S, Simon G, Repetto M, "et al." |title=Sequencing analysis of forty-eight human image cDNA clones similar to Drosophila mutant protein. |journal=DNA Seq. |volume=9 |issue= 5-6 |pages= 307–15 |year= 1999 |pmid= 10524757 |doi=
*cite journal | author=Schönherr R, Gessner G, Löber K, Heinemann SH |title=Functional distinction of human EAG1 and EAG2 potassium channels. |journal=FEBS Lett. |volume=514 |issue= 2-3 |pages= 204–8 |year= 2002 |pmid= 11943152 |doi=
*cite journal | author=Ju M, Wray D |title=Molecular identification and characterisation of the human eag2 potassium channel. |journal=FEBS Lett. |volume=524 |issue= 1-3 |pages= 204–10 |year= 2002 |pmid= 12135768 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Otsuki T, Ota T, Nishikawa T, "et al." |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117PBB_Controls
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