Rosenthal fiber

Rosenthal fiber

A Rosenthal fiber is a thick, elongated, worm-like or "corkscrew" eosinophilic (pink) bundle that is found on H&E staining of the brain in the presence of long standing gliosis, occasional tumors, and some metabolic disorders. Its presence is pathognomonic of either pilocytic astrocytoma (more common) or Alexander's disease (a rare leukodystrophy). The fibers are found in astrocytic processes and are thought to be clumped intermediate filament proteins.

=References=
* Neuropathology Mini-Course. [http://www.pathology.vcu.edu/WirSelfInst/tumor-2.html Chapter 9 - Tumors of the Nervous System]
* [http://www.thedoctorsdoctor.com/bodysites/brainandspinalcord.htm Doctor's Doctor - Brain and Spinal Cord]
* [http://ajp.amjpathol.org/cgi/content/abstract/130/3/569 Isolation of a major protein component of Rosenthal fibers]


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Rosenthal fiber — See under fiber …   Medical dictionary

  • Fiber — The parts of plants that cannot be digested, namely complex carbohydrates. Also known as bulk or roughage. Complex carbohydrates from plants are rich in starch and fiber. Examples of plants that provide complex carbohydrates (fiber) are fresh… …   Medical dictionary

  • Leukodystrophy — A disorder of the white matter of the brain, the part of the brain that contains myelinated nerve fibers. The white matter is white because it is the color of myelin, the insulation covering the nerve fibers. (The white matter is as opposed to… …   Medical dictionary

  • Ubiquitin — is a highly conserved regulatory protein that is expressed in eukaryotes. Ubiquitination (or ubiquitylation) refers to the post translational modification of a protein by the covalent attachment (via an isopeptide bond) of one or more ubiquitin… …   Wikipedia

  • Dosimeter — Fiber dosimeter (see gallery below for view through dosimeter) Dosimeters measure an individual s or an object s[1] exposure to something in the environment particularly to a hazard inflicting cumulative impact over long periods of time, or over… …   Wikipedia

  • USS Iowa turret explosion — USS Iowa s Turret Two explodes Date April 19, 1989 Place Caribbean Sea ne …   Wikipedia

  • Anthony Spilotro — 1974 FBI mugshot of Spilotro Born May 19, 1938(1938 05 19) Chicago, Illinois, U.S. Died …   Wikipedia

  • Potato — Irish potato redirects here. For the confectionery, see Irish potato candy. For other uses, see Potato (disambiguation). Potato …   Wikipedia

  • Cannabis cultivation — Typical home grown organic sinsemilla bud compared to a cigarette pack. This article presents common techniques and facts regarding the cultivation of the flowering plant cannabis, primarily for the production and consumption of marijuana buds.… …   Wikipedia

  • Myosatellite cell — For the glial progenitor cells, see Satellite cell (glial). Myosatellite cell Latin myosatellitocytus Code TH H2.00.05.2.01020 Myosatellite cells or satellite cells are small mononuclear progenitor cells with virtually no cytoplasm found in… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”