PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
Identifiers
Symbols	PDS5A; DKFZp686B19246; FLJ41012; KIAA0648; MGC131948; MGC161503; SCC-112
External IDs	OMIM: 613200 MGI: 1918771 HomoloGene: 22877 GeneCards: PDS5A Gene
Gene Ontology Molecular function • protein binding • identical protein binding Cellular component • chromatin • nucleus Biological process • cell cycle • mitosis • negative regulation of DNA replication • cell division Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23244	71521
Ensembl	ENSG00000121892	ENSMUSG00000029202
UniProt	Q29RF7	n/a
RefSeq (mRNA)	NM_001100399.1	NM_001081321.1
RefSeq (protein)	NP_001093869.1	NP_001074790.1
Location (UCSC)	Chr 4: 39.82 – 39.98 Mb	Chr 5: 66.01 – 66.09 Mb
PubMed search	[1]	[2]

Sister chromatid cohesion protein PDS5 homolog A is a protein that in humans is encoded by the PDS5A gene.^[1][2][3]

References

1. ^ Sumara I, Vorlaufer E, Gieffers C, Peters BH, Peters JM (Dec 2000). "Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase". J Cell Biol 151 (4): 749–62. doi:10.1083/jcb.151.4.749. PMC 2169443. PMID 11076961. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2169443. 
2. ^ Losada A, Yokochi T, Hirano T (May 2005). "Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts". J Cell Sci 118 (Pt 10): 2133–41. doi:10.1242/jcs.02355. PMID 15855230. 
3. ^ "Entrez Gene: SCC-112 SCC-112 protein". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23244. 

Further reading

• Ishikawa K, Nagase T, Suyama M et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811. 
• Gregson HC, Schmiesing JA, Kim JS et al. (2002). "A potential role for human cohesin in mitotic spindle aster assembly". J. Biol. Chem. 276 (50): 47575–82. doi:10.1074/jbc.M103364200. PMID 11590136. 
• Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Kumar D, Sakabe I, Patel S et al. (2004). "SCC-112, a novel cell cycle-regulated molecule, exhibits reduced expression in human renal carcinomas". Gene 328: 187–96. doi:10.1016/j.gene.2003.12.013. PMID 15019998. 
• Rankin S, Ayad NG, Kirschner MW (2005). "Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates". Mol. Cell 18 (2): 185–200. doi:10.1016/j.molcel.2005.03.017. PMID 15837422. 
• Ewing RM, Chu P, Elisma F et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.