- SLC29A4
Solute carrier family 29 (nucleoside transporters), member 4, also known as SLC29A4, is a human
gene .cite web | title = Entrez Gene: SLC29A4 solute carrier family 29 (nucleoside transporters), member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=222962| accessdate = ]PBB_Summary
section_title =
summary_text = This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized.cite web | title = Entrez Gene: SLC29A4 solute carrier family 29 (nucleoside transporters), member 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=222962| accessdate = ]ee also
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Solute carrier family References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Baldwin SA, Beal PR, Yao SY, "et al." |title=The equilibrative nucleoside transporter family, SLC29. |journal=Pflugers Arch. |volume=447 |issue= 5 |pages= 735–43 |year= 2004 |pmid= 12838422 |doi= 10.1007/s00424-003-1103-2
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Engel K, Zhou M, Wang J |title=Identification and characterization of a novel monoamine transporter in the human brain. |journal=J. Biol. Chem. |volume=279 |issue= 48 |pages= 50042–9 |year= 2005 |pmid= 15448143 |doi= 10.1074/jbc.M407913200
*cite journal | author=Engel K, Wang J |title=Interaction of organic cations with a newly identified plasma membrane monoamine transporter. |journal=Mol. Pharmacol. |volume=68 |issue= 5 |pages= 1397–407 |year= 2005 |pmid= 16099839 |doi= 10.1124/mol.105.016832
*cite journal | author=Barnes K, Dobrzynski H, Foppolo S, "et al." |title=Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH. |journal=Circ. Res. |volume=99 |issue= 5 |pages= 510–9 |year= 2006 |pmid= 16873718 |doi= 10.1161/01.RES.0000238359.18495.42
*cite journal | author=Xia L, Engel K, Zhou M, Wang J |title=Membrane localization and pH-dependent transport of a newly cloned organic cation transporter (PMAT) in kidney cells. |journal=Am. J. Physiol. Renal Physiol. |volume=292 |issue= 2 |pages= F682–90 |year= 2007 |pmid= 17018840 |doi= 10.1152/ajprenal.00302.2006
*cite journal | author=Zhou M, Xia L, Engel K, Wang J |title=Molecular determinants of substrate selectivity of a novel organic cation transporter (PMAT) in the SLC29 family. |journal=J. Biol. Chem. |volume=282 |issue= 5 |pages= 3188–95 |year= 2007 |pmid= 17121826 |doi= 10.1074/jbc.M609421200
*cite journal | author=Bottalico B, Noskova V, Pilka R, "et al." |title=The organic cation transporters (OCT1, OCT2, EMT) and the plasma membrane monoamine transporter (PMAT) show differential distribution and cyclic expression pattern in human endometrium and early pregnancy decidua. |journal=Mol. Reprod. Dev. |volume=74 |issue= 10 |pages= 1303–11 |year= 2007 |pmid= 17393420 |doi= 10.1002/mrd.20697PBB_Controls
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