- B3GAT2
Beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S), also known as B3GAT2, is a human
gene .cite web | title = Entrez Gene: B3GAT2 beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=135152| accessdate = ]PBB_Summary
section_title =
summary_text = The product of this gene is a transmembrane protein belonging to the glucuronyltransferase family, and catalyzes the transfer of a beta-1,3 linked glucuronic acid to a terminal galactose in different glycoproteins or glycolipids containing a Gal-beta-1-4GlcNAc or Gal-beta-1-3GlcNAc residue. The encoded protein is involved in the synthesis of the human natural killer-1 (HNK-1) carbohydrate epitope, a sulfated trisaccharide implicated in cellular migration and adhesion in the nervous system.cite web | title = Entrez Gene: B3GAT2 beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=135152| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Nagase T, Kikuno R, Ohara O |title=Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. |journal=DNA Res. |volume=8 |issue= 6 |pages= 319–27 |year= 2002 |pmid= 11853319 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Marcos I, Galán JJ, Borrego S, Antiñolo G |title=Cloning, characterization, and chromosome mapping of the human GlcAT-S gene. |journal=J. Hum. Genet. |volume=47 |issue= 12 |pages= 677–80 |year= 2003 |pmid= 12522689 |doi= 10.1007/s100380200103
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Kakuda S, Oka S, Kawasaki T |title=Purification and characterization of two recombinant human glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate in Escherichia coli. |journal=Protein Expr. Purif. |volume=35 |issue= 1 |pages= 111–9 |year= 2004 |pmid= 15039073 |doi= 10.1016/j.pep.2003.12.021
*cite journal | author=Kakuda S, Sato Y, Tonoyama Y, "et al." |title=Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate. |journal=Glycobiology |volume=15 |issue= 2 |pages= 203–10 |year= 2005 |pmid= 15470230 |doi= 10.1093/glycob/cwi001
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Shiba T, Kakuda S, Ishiguro M, "et al." |title=Crystal structure of GlcAT-S, a human glucuronyltransferase, involved in the biosynthesis of the HNK-1 carbohydrate epitope. |journal=Proteins |volume=65 |issue= 2 |pages= 499–508 |year= 2006 |pmid= 16897771 |doi= 10.1002/prot.21118PBB_Controls
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