DIXDC1

DIX domain containing 1
Identifiers
Symbols	DIXDC1; CCD1; KIAA1735
External IDs	OMIM: 610493 MGI: 2679721 HomoloGene: 82369 GeneCards: DIXDC1 Gene
Gene Ontology Molecular function • actin binding • signal transducer activity • protein domain specific binding • gamma-tubulin binding Cellular component • intracellular • cytoplasm • cytosol • focal adhesion • cell junction Biological process • multicellular organismal development • Wnt receptor signaling pathway • positive regulation of canonical Wnt receptor signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	85458	330938
Ensembl	ENSG00000150764	ENSMUSG00000032064
UniProt	Q155Q3	n/a
RefSeq (mRNA)	NM_001037954.2	NM_178118.2
RefSeq (protein)	NP_001033043.1	NP_835219.1
Location (UCSC)	Chr 11: 111.8 – 111.89 Mb	Chr 9: 50.47 – 50.55 Mb
PubMed search	[1]	[2]

Dixin is a protein that in humans is encoded by the DIXDC1 gene.^[1][2]

References

1. ^ Katoh M, Katoh M (Jun 2003). "KIAA1735 gene on human chromosome 11q23.1 encodes a novel protein with myosine-tail homologous domain and C-terminal DIX domain". Int J Oncol 23 (1): 145–50. PMID 12792787. 
2. ^ "Entrez Gene: DIXDC1 DIX domain containing 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=85458. 

Further reading

• Andersson B, Wentland MA, Ricafrente JY et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
• Yu W, Andersson B, Worley KC et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139146. 
• Nagase T, Kikuno R, Hattori A et al. (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970. 
• Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ohira M, Morohashi A, Inuzuka H et al. (2003). "Expression profiling and characterization of 4200 genes cloned from primary neuroblastomas: identification of 305 genes differentially expressed between favorable and unfavorable subsets". Oncogene 22 (35): 5525–36. doi:10.1038/sj.onc.1206853. PMID 12934113. 
• Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Wong CK, Luo W, Deng Y et al. (2004). "The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms". J. Biol. Chem. 279 (38): 39366–73. doi:10.1074/jbc.M404598200. PMID 15262978. 
• Kimura K, Wakamatsu A, Suzuki Y et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129. 
• Wang X, Zheng L, Zeng Z et al. (2006). "DIXDC1 isoform, l-DIXDC1, is a novel filamentous actin-binding protein". Biochem. Biophys. Res. Commun. 347 (1): 22–30. doi:10.1016/j.bbrc.2006.06.050. PMID 16814745.