DEFB106A

DEFB106A
Defensin, beta 106A
Identifiers
Symbols DEFB106A; BD-6; DEFB-6; DEFB106; MGC118938; MGC118939; MGC118940; MGC118941; MGC133011; MGC133012
External IDs MGI2179202 HomoloGene77225 GeneCards: DEFB106A Gene
Orthologs
Species Human Mouse
Entrez 245909 246082
Ensembl n/a ENSMUSG00000048500
UniProt Q8N104 Q8R2I5
RefSeq (mRNA) NM_152251 NM_139222.3
RefSeq (protein) NP_689464 NP_631968.1
Location (UCSC) n/a Chr 8:
23.04 – 23.04 Mb
PubMed search [1] [2]

Beta-defensin 106 is a protein that in humans is encoded by the DEFB106A gene.[1][2]

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy.[2]

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Further reading