DOPEY2

Dopey family member 2
Identifiers
Symbols	DOPEY2; 21orf5; C21orf5
External IDs	OMIM: 604803 MGI: 1917278 HomoloGene: 21068 GeneCards: DOPEY2 Gene
Gene Ontology Molecular function • molecular_function Cellular component • Golgi membrane Biological process • Golgi to endosome transport • endoplasmic reticulum organization • multicellular organismal development • protein transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9980	70028
Ensembl	ENSG00000142197	ENSMUSG00000022946
UniProt	Q9Y3R5	n/a
RefSeq (mRNA)	NM_005128	NM_026700
RefSeq (protein)	NP_005119	NP_080976
Location (UCSC)	Chr 21: 37.53 – 37.71 Mb	Chr 16: 93.71 – 93.81 Mb
PubMed search	[1]	[2]

Protein dopey-2 is a protein that in humans is encoded by the DOPEY2 gene.^[1][2][3][4]

References

1. ^ Gillingham AK, Whyte JR, Panic B, Munro S (Jan 2006). "Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus". J Biol Chem 281 (4): 2273–80. doi:10.1074/jbc.M510176200. PMID 16301316. 
2. ^ Rachidi M, Lopes C, Costantine M, Delabar JM (Nov 2005). "C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome". DNA Res 12 (3): 203–10. doi:10.1093/dnares/dsi004. PMID 16303751. 
3. ^ Pascon RC, Miller BL (Dec 2000). "Morphogenesis in Aspergillus nidulans requires Dopey (DopA), a member of a novel family of leucine zipper-like proteins conserved from yeast to humans". Mol Microbiol 36 (6): 1250–64. doi:10.1046/j.1365-2958.2000.01950.x. PMID 10931277. 
4. ^ "Entrez Gene: DOPEY2 dopey family member 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9980. 

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954. 
• Dahmane N, Ghezala GA, Gosset P, et al. (1998). "Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.". Genomics 48 (1): 12–23. doi:10.1006/geno.1997.5146. PMID 9503011. 
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032. 
• Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953. 
• Guipponi M, Brunschwig K, Chamoun Z, et al. (2001). "C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning.". Genomics 68 (1): 30–40. doi:10.1006/geno.2000.6250. PMID 10950924. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Lopes C, Chettouh Z, Delabar JM, Rachidi M (2003). "The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice.". Biochem. Biophys. Res. Commun. 305 (4): 915–24. doi:10.1016/S0006-291X(03)00867-2. PMID 12767918. 
• Rachidi M, Lopes C, Delezoide AL, Delabar JM (2006). "C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down syndrome.". Cytogenet. Genome Res. 112 (1-2): 16–22. doi:10.1159/000087509. PMID 16276086.