ATP1B3

ATPase, Na+/K+ transporting, beta 3 polypeptide, also known as ATP1B3, is a human gene.cite web | title = Entrez Gene: ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=483| accessdate = ] ATP1B3 has also been designated as CD298 (cluster of differentiation 298).

PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.cite web | title = Entrez Gene: ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=483| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lingrel JB, Orlowski J, Shull MM, Price EM |title=Molecular genetics of Na,K-ATPase. |journal=Prog. Nucleic Acid Res. Mol. Biol. |volume=38 |issue= |pages= 37–89 |year= 1990 |pmid= 2158121 |doi=
*cite journal | author=Jørgensen PL |title=Mechanism of the Na+, K+ pump. Protein structure and conformations of the pure (Na+ +K+)-ATPase. |journal=Biochim. Biophys. Acta |volume=694 |issue= 1 |pages= 27–68 |year= 1982 |pmid= 6289898 |doi=
*cite journal | author=Malik N, Canfield VA, Beckers MC, "et al." |title=Identification of the mammalian Na,K-ATPase 3 subunit. |journal=J. Biol. Chem. |volume=271 |issue= 37 |pages= 22754–8 |year= 1996 |pmid= 8798450 |doi=
*cite journal | author=Malik N, Canfield V, Sanchez-Watts G, "et al." |title=Structural organization and chromosomal localization of the human Na,K-ATPase beta 3 subunit gene and pseudogene. |journal=Mamm. Genome |volume=9 |issue= 2 |pages= 136–43 |year= 1998 |pmid= 9457675 |doi=
*cite journal | author=Chiampanichayakul S, Szekeres A, Khunkaewla P, "et al." |title=Engagement of Na,K-ATPase beta3 subunit by a specific mAb suppresses T and B lymphocyte activation. |journal=Int. Immunol. |volume=14 |issue= 12 |pages= 1407–14 |year= 2003 |pmid= 12456588 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhang H, Li XJ, Martin DB, Aebersold R |title=Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. |journal=Nat. Biotechnol. |volume=21 |issue= 6 |pages= 660–6 |year= 2003 |pmid= 12754519 |doi= 10.1038/nbt827
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Chi A, Valencia JC, Hu ZZ, "et al." |title=Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. |journal=J. Proteome Res. |volume=5 |issue= 11 |pages= 3135–44 |year= 2007 |pmid= 17081065 |doi= 10.1021/pr060363j
*cite journal | author=Chiampanichayakul S, Khunkaewla P, Pata S, Kasinrerk W |title=Na, K ATPase beta3 subunit (CD298): association with alpha subunit and expression on peripheral blood cells. |journal=Tissue Antigens |volume=68 |issue= 6 |pages= 509–17 |year= 2007 |pmid= 17176442 |doi= 10.1111/j.1399-0039.2006.00726.x
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Aughey RJ, Murphy KT, Clark SA, "et al." |title=Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes. |journal=J. Appl. Physiol. |volume=103 |issue= 1 |pages= 39–47 |year= 2007 |pmid= 17446412 |doi= 10.1152/japplphysiol.00236.2006

External links

*

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes