MID2

Midline 2, also known as MID2, is a human gene.cite web | title = Entrez Gene: MID2 midline 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11043| accessdate = ]

PBB_Summary
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summary_text = The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Its function has not been identified. Alternate splicing of this gene results in two transcript variants encoding different isoforms.cite web | title = Entrez Gene: MID2 midline 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11043| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Jehee FS, Rosenberg C, Krepischi-Santos AC, "et al." |title=An Xq22.3 duplication detected by comparative genomic hybridization microarray (Array-CGH) defines a new locus (FGS5) for FG syndrome. |journal=Am. J. Med. Genet. A |volume=139 |issue= 3 |pages= 221–6 |year= 2006 |pmid= 16283679 |doi= 10.1002/ajmg.a.30991
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Yap MW, Nisole S, Lynch C, Stoye JP |title=Trim5alpha protein restricts both HIV-1 and murine leukemia virus. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 29 |pages= 10786–91 |year= 2004 |pmid= 15249690 |doi= 10.1073/pnas.0402876101
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Short KM, Hopwood B, Yi Z, Cox TC |title=MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders. |journal=BMC Cell Biol. |volume=3 |issue= |pages= 1 |year= 2002 |pmid= 11806752 |doi=
*cite journal | author=Reymond A, Meroni G, Fantozzi A, "et al." |title=The tripartite motif family identifies cell compartments. |journal=EMBO J. |volume=20 |issue= 9 |pages= 2140–51 |year= 2001 |pmid= 11331580 |doi= 10.1093/emboj/20.9.2140
*cite journal | author=Perry J, Short KM, Romer JT, "et al." |title=FXY2/MID2, a gene related to the X-linked Opitz syndrome gene FXY/MID1, maps to Xq22 and encodes an FNIII domain-containing protein that associates with microtubules. |journal=Genomics |volume=62 |issue= 3 |pages= 385–94 |year= 2000 |pmid= 10644436 |doi= 10.1006/geno.1999.6043
*cite journal | author=Buchner G, Montini E, Andolfi G, "et al." |title=MID2, a homologue of the Opitz syndrome gene MID1: similarities in subcellular localization and differences in expression during development. |journal=Hum. Mol. Genet. |volume=8 |issue= 8 |pages= 1397–407 |year= 1999 |pmid= 10400986 |doi=
*cite journal | author=Cainarca S, Messali S, Ballabio A, Meroni G |title=Functional characterization of the Opitz syndrome gene product (midin): evidence for homodimerization and association with microtubules throughout the cell cycle. |journal=Hum. Mol. Genet. |volume=8 |issue= 8 |pages= 1387–96 |year= 1999 |pmid= 10400985 |doi=

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