USP18

USP18

Ubiquitin specific peptidase 18 (USP18), also known as UBP43, is a gene.cite web | title = Entrez Gene: USP18 ubiquitin specific peptidase 18| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11274| accessdate = ]

PBB_Summary
section_title =
summary_text = USP18, a member of the deubiquitinating protease family of enzymes, is thought to remove ISG15 adducts from a broad range of protein substrates. [supplied by OMIM] cite web | title = Entrez Gene: USP18 ubiquitin specific peptidase 18| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11274| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Puente XS, Sánchez LM, Overall CM, López-Otín C |title=Human and mouse proteases: a comparative genomic approach. |journal=Nat. Rev. Genet. |volume=4 |issue= 7 |pages= 544–58 |year= 2003 |pmid= 12838346 |doi= 10.1038/nrg1111
*cite journal | author=Li XL, Blackford JA, Judge CS, "et al." |title=RNase-L-dependent destabilization of interferon-induced mRNAs. A role for the 2-5A system in attenuation of the interferon response. |journal=J. Biol. Chem. |volume=275 |issue= 12 |pages= 8880–8 |year= 2000 |pmid= 10722734 |doi=
*cite journal | author=Schwer H, Liu LQ, Zhou L, "et al." |title=Cloning and characterization of a novel human ubiquitin-specific protease, a homologue of murine UBP43 (Usp18). |journal=Genomics |volume=65 |issue= 1 |pages= 44–52 |year= 2000 |pmid= 10777664 |doi= 10.1006/geno.2000.6148
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Kang D, Jiang H, Wu Q, "et al." |title=Cloning and characterization of human ubiquitin-processing protease-43 from terminally differentiated human melanoma cells using a rapid subtraction hybridization protocol RaSH. |journal=Gene |volume=267 |issue= 2 |pages= 233–42 |year= 2001 |pmid= 11313150 |doi=
*cite journal | author=Malakhov MP, Malakhova OA, Kim KI, "et al." |title=UBP43 (USP18) specifically removes ISG15 from conjugated proteins. |journal=J. Biol. Chem. |volume=277 |issue= 12 |pages= 9976–81 |year= 2002 |pmid= 11788588 |doi= 10.1074/jbc.M109078200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Tokarz S, Berset C, La Rue J, "et al." |title=The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCFSkp2 ubiquitin ligase. |journal=J. Biol. Chem. |volume=279 |issue= 45 |pages= 46424–30 |year= 2004 |pmid= 15342634 |doi= 10.1074/jbc.M403189200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Yan M, Luo JK, Ritchie KJ, "et al." |title=Ubp43 regulates BCR-ABL leukemogenesis via the type 1 interferon receptor signaling. |journal=Blood |volume=110 |issue= 1 |pages= 305–12 |year= 2007 |pmid= 17374743 |doi= 10.1182/blood-2006-07-033209

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Look at other dictionaries:

  • Deubiquitinating enzyme — Deubiquitinating enzymes (DUBs) are a large group of proteases[1] (more than 60 known) that regulate ubiquitin dependent metabolic pathways by cleaving ubiquitin protein bonds. DUBs are also commonly referred to as deubiquitinating peptidases,… …   Wikipedia

  • ISG15 — ubiquitin like modifier, also known as ISG15, is a human gene. [cite web | title = Entrez Gene: ISG15 ISG15 ubiquitin like modifier| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=9636| accessdate = ] ISG15 …   Wikipedia

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