[cite web | title = Entrez Gene: HCN4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10021| accessdate = ] ] PBB_Summary
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ee also
* Cyclic nucleotide-gated ion channel
References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Hofmann F, Biel M, Kaupp UB |title=International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 455–62 |year= 2006 |pmid= 16382102 |doi= 10.1124/pr.57.4.8
*cite journal | author=Ludwig A, Zong X, Stieber J, "et al." |title=Two pacemaker channels from human heart with profoundly different activation kinetics. |journal=EMBO J. |volume=18 |issue= 9 |pages= 2323–9 |year= 1999 |pmid= 10228147 |doi= 10.1093/emboj/18.9.2323
*cite journal | author=Seifert R, Scholten A, Gauss R, "et al." |title=Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 16 |pages= 9391–6 |year= 1999 |pmid= 10430953 |doi=
*cite journal | author=Qu J, Altomare C, Bucchi A, "et al." |title=Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells. |journal=Pflugers Arch. |volume=444 |issue= 5 |pages= 597–601 |year= 2003 |pmid= 12194012 |doi= 10.1007/s00424-002-0860-7
*cite journal | author=Schulze-Bahr E, Neu A, Friederich P, "et al." |title=Pacemaker channel dysfunction in a patient with sinus node disease. |journal=J. Clin. Invest. |volume=111 |issue= 10 |pages= 1537–45 |year= 2003 |pmid= 12750403 |doi=
*cite journal | author=Stieber J, Thomer A, Much B, "et al." |title=Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4. |journal=J. Biol. Chem. |volume=278 |issue= 36 |pages= 33672–80 |year= 2003 |pmid= 12813043 |doi= 10.1074/jbc.M305318200
*cite journal | author=Decher N, Bundis F, Vajna R, Steinmeyer K |title=KCNE2 modulates current amplitudes and activation kinetics of HCN4: influence of KCNE family members on HCN4 currents. |journal=Pflugers Arch. |volume=446 |issue= 6 |pages= 633–40 |year= 2004 |pmid= 12856183 |doi= 10.1007/s00424-003-1127-7
*cite journal | author=Much B, Wahl-Schott C, Zong X, "et al." |title=Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels. |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 43781–6 |year= 2003 |pmid= 12928435 |doi= 10.1074/jbc.M306958200
*cite journal | author=Ueda K, Nakamura K, Hayashi T, "et al." |title=Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia. |journal=J. Biol. Chem. |volume=279 |issue= 26 |pages= 27194–8 |year= 2004 |pmid= 15123648 |doi= 10.1074/jbc.M311953200
*cite journal | author=Michels G, Er F, Khan I, "et al." |title=Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias. |journal=Circulation |volume=111 |issue= 4 |pages= 399–404 |year= 2005 |pmid= 15687126 |doi= 10.1161/01.CIR.0000153799.65783.3A
*cite journal | author=Milanesi R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D |title=Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel. |journal=N. Engl. J. Med. |volume=354 |issue= 2 |pages= 151–7 |year= 2006 |pmid= 16407510 |doi= 10.1056/NEJMoa052475
*cite journal | author=Elinder F, Männikkö R, Pandey S, Larsson HP |title=Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels. |journal=J. Physiol. (Lond.) |volume=575 |issue= Pt 2 |pages= 417–31 |year= 2006 |pmid= 16777944 |doi= 10.1113/jphysiol.2006.110437
*cite journal | author=Nof E, Luria D, Brass D, "et al." |title=Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia. |journal=Circulation |volume=116 |issue= 5 |pages= 463–70 |year= 2007 |pmid= 17646576 |doi= 10.1161/CIRCULATIONAHA.107.706887
External links
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