[cite web | title = Entrez Gene: HCN2 hyperpolarization activated cyclic nucleotide-gated potassium channel 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=610| accessdate = ] ] PBB_Summary
section_title =
summary_text =
ee also
* Cyclic nucleotide-gated ion channel
References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Hofmann F, Biel M, Kaupp UB |title=International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels. |journal=Pharmacol. Rev. |volume=57 |issue= 4 |pages= 455–62 |year= 2006 |pmid= 16382102 |doi= 10.1124/pr.57.4.8
*cite journal | author=Santoro B, Grant SG, Bartsch D, Kandel ER |title=Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to eag and cyclic nucleotide-gated channels. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 26 |pages= 14815–20 |year= 1998 |pmid= 9405696 |doi=
*cite journal | author=Santoro B, Liu DT, Yao H, "et al." |title=Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. |journal=Cell |volume=93 |issue= 5 |pages= 717–29 |year= 1998 |pmid= 9630217 |doi=
*cite journal | author=Kleiderlein JJ, Nisson PE, Jessee J, "et al." |title=CCG repeats in cDNAs from human brain. |journal=Hum. Genet. |volume=103 |issue= 6 |pages= 666–73 |year= 1999 |pmid= 9921901 |doi=
*cite journal | author=Ludwig A, Zong X, Stieber J, "et al." |title=Two pacemaker channels from human heart with profoundly different activation kinetics. |journal=EMBO J. |volume=18 |issue= 9 |pages= 2323–9 |year= 1999 |pmid= 10228147 |doi= 10.1093/emboj/18.9.2323
*cite journal | author=Vaccari T, Moroni A, Rocchi M, "et al." |title=The human gene coding for HCN2, a pacemaker channel of the heart. |journal=Biochim. Biophys. Acta |volume=1446 |issue= 3 |pages= 419–25 |year= 1999 |pmid= 10524219 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Ulens C, Tytgat J |title=Functional heteromerization of HCN1 and HCN2 pacemaker channels. |journal=J. Biol. Chem. |volume=276 |issue= 9 |pages= 6069–72 |year= 2001 |pmid= 11133998 |doi= 10.1074/jbc.C000738200
*cite journal | author=Proenza C, Tran N, Angoli D, "et al." |title=Different roles for the cyclic nucleotide binding domain and amino terminus in assembly and expression of hyperpolarization-activated, cyclic nucleotide-gated channels. |journal=J. Biol. Chem. |volume=277 |issue= 33 |pages= 29634–42 |year= 2002 |pmid= 12034718 |doi= 10.1074/jbc.M200504200
*cite journal | author=Qu J, Altomare C, Bucchi A, "et al." |title=Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells. |journal=Pflugers Arch. |volume=444 |issue= 5 |pages= 597–601 |year= 2003 |pmid= 12194012 |doi= 10.1007/s00424-002-0860-7
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Sesti F, Rajan S, Gonzalez-Colaso R, "et al." |title=Hyperpolarization moves S4 sensors inward to open MVP, a methanococcal voltage-gated potassium channel. |journal=Nat. Neurosci. |volume=6 |issue= 4 |pages= 353–61 |year= 2003 |pmid= 12640457 |doi= 10.1038/nn1028
*cite journal | author=Stieber J, Thomer A, Much B, "et al." |title=Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4. |journal=J. Biol. Chem. |volume=278 |issue= 36 |pages= 33672–80 |year= 2003 |pmid= 12813043 |doi= 10.1074/jbc.M305318200
*cite journal | author=Bender RA, Soleymani SV, Brewster AL, "et al." |title=Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus. |journal=J. Neurosci. |volume=23 |issue= 17 |pages= 6826–36 |year= 2003 |pmid= 12890777 |doi=
*cite journal | author=Much B, Wahl-Schott C, Zong X, "et al." |title=Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels. |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 43781–6 |year= 2003 |pmid= 12928435 |doi= 10.1074/jbc.M306958200
*cite journal | author=Grimwood J, Gordon LA, Olsen A, "et al." |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399
*cite journal | author=Michels G, Er F, Khan I, "et al." |title=Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias. |journal=Circulation |volume=111 |issue= 4 |pages= 399–404 |year= 2005 |pmid= 15687126 |doi= 10.1161/01.CIR.0000153799.65783.3A
*cite journal | author=Akhavan A, Atanasiu R, Noguchi T, "et al." |title=Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization. |journal=J. Cell. Sci. |volume=118 |issue= Pt 13 |pages= 2803–12 |year= 2005 |pmid= 15961404 |doi= 10.1242/jcs.02423
*cite journal | author=Calloe K, Elmedyb P, Olesen SP, "et al." |title=Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels. |journal=Biophys. J. |volume=89 |issue= 3 |pages= 2159–69 |year= 2006 |pmid= 15980171 |doi= 10.1529/biophysj.105.063792
External links
*
PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
