NUCKS1

Nuclear casein kinase and cyclin-dependent kinase substrate 1
Identifiers
Symbols	NUCKS1; FLJ21480; FLJ32016; FLJ38536; NUCKS
External IDs	OMIM: 611912 MGI: 1934811 HomoloGene: 23377 GeneCards: NUCKS1 Gene
Gene Ontology Cellular component • nucleus Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	64710	98415
Ensembl	ENSG00000069275	ENSMUSG00000026434
UniProt	Q9H1E3	Q80XU3
RefSeq (mRNA)	NM_022731	NM_175294
RefSeq (protein)	NP_073568	NP_780503
Location (UCSC)	Chr 1: 205.68 – 205.72 Mb	Chr 1: 133.81 – 133.83 Mb
PubMed search	[1]	[2]

Nuclear ubiquitous casein and cyclin-dependent kinases substrate is a protein that in humans is encoded by the NUCKS1 gene.^[1][2]

References

1. ^ Ostvold AC, Norum JH, Mathiesen S, Wanvik B, Sefland I, Grundt K (Apr 2001). "Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo". Eur J Biochem 268 (8): 2430–40. doi:10.1046/j.1432-1327.2001.02120.x. PMID 11298763. 
2. ^ "Entrez Gene: NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=64710. 

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
• Thompson HG, Harris JW, Wold BJ, et al. (2003). "Identification and confirmation of a module of coexpressed genes.". Genome Res. 12 (10): 1517–22. doi:10.1101/gr.418402. PMC 187523. PMID 12368243. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=187523. 
• Grundt K, Skjeldal L, Anthonsen HW, et al. (2002). "A putative DNA-binding domain in the NUCKS protein.". Arch. Biochem. Biophys. 407 (2): 168–75. doi:10.1016/S0003-9861(02)00513-1. PMID 12413487. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=514446. 
• Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747. 
• Grundt K, Haga IV, Aleporou-Marinou V, et al. (2004). "Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species.". Biochem. Biophys. Res. Commun. 323 (3): 796–801. doi:10.1016/j.bbrc.2004.08.153. PMID 15381070. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Gevaert K, Staes A, Van Damme J, et al. (2006). "Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC.". Proteomics 5 (14): 3589–99. doi:10.1002/pmic.200401217. PMID 16097034. 
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. 
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
• Grundt K, Haga IV, Huitfeldt HS, Ostvold AC (2007). "Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS.". Biochim. Biophys. Acta 1773 (9): 1398–406. doi:10.1016/j.bbamcr.2007.05.013. PMID 17604136.