TCF21 (gene)

Transcription factor 21, also known as TCF21, is a human gene.cite web | title = Entrez Gene: TCF21 transcription factor 21| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6943| accessdate = ]

PBB_Summary
section_title =
summary_text = TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: TCF21 transcription factor 21| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6943| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Littlewood TD, Evan GI |title=Transcription factors 2: helix-loop-helix. |journal=Protein profile |volume=2 |issue= 6 |pages= 621–702 |year= 1995 |pmid= 7553065 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Quaggin SE, Vanden Heuvel GB, Igarashi P |title=Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney. |journal=Mech. Dev. |volume=71 |issue= 1-2 |pages= 37–48 |year= 1998 |pmid= 9507058 |doi=
*cite journal | author=Hidai H, Bardales R, Goodwin R, "et al." |title=Cloning of capsulin, a basic helix-loop-helix factor expressed in progenitor cells of the pericardium and the coronary arteries. |journal=Mech. Dev. |volume=73 |issue= 1 |pages= 33–43 |year= 1998 |pmid= 9545526 |doi=
*cite journal | author=Robb L, Mifsud L, Hartley L, "et al." |title=epicardin: A novel basic helix-loop-helix transcription factor gene expressed in epicardium, branchial arch myoblasts, and mesenchyme of developing lung, gut, kidney, and gonads. |journal=Dev. Dyn. |volume=213 |issue= 1 |pages= 105–13 |year= 1999 |pmid= 9733105 |doi= 10.1002/(SICI)1097-0177(199809)213:1<105::AID-AJA10>3.0.CO;2-1 |doilabel=10.1002/(SICI)1097-0177(199809)213:1105::AID-AJA103.0.CO;2-1
*cite journal | author=Quaggin SE, Schwartz L, Cui S, "et al." |title=The basic-helix-loop-helix protein pod1 is critically important for kidney and lung organogenesis. |journal=Development |volume=126 |issue= 24 |pages= 5771–83 |year= 2000 |pmid= 10572052 |doi=
*cite journal | author=Suzuki H, Fukunishi Y, Kagawa I, "et al." |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758–65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Funato N, Ohyama K, Kuroda T, Nakamura M |title=Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7486–93 |year= 2003 |pmid= 12493738 |doi= 10.1074/jbc.M212248200
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Smith LT, Lin M, Brena RM, "et al." |title=Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 4 |pages= 982–7 |year= 2006 |pmid= 16415157 |doi= 10.1073/pnas.0510171102

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