ATP5C1

ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1, also known as ATP5C1, is a human gene.cite web | title = Entrez Gene: ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=509| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14.cite web | title = Entrez Gene: ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=509| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yoshida M, Muneyuki E, Hisabori T |title=ATP synthase--a marvellous rotary engine of the cell. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 9 |pages= 669–77 |year= 2001 |pmid= 11533724 |doi= 10.1038/35089509
*cite journal | author=Abrahams JP, Leslie AG, Lutter R, Walker JE |title=Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria. |journal=Nature |volume=370 |issue= 6491 |pages= 621–8 |year= 1994 |pmid= 8065448 |doi= 10.1038/370621a0
*cite journal | author=Jabs EW, Thomas PJ, Bernstein M, "et al." |title=Chromosomal localization of genes required for the terminal steps of oxidative metabolism: alpha and gamma subunits of ATP synthase and the phosphate carrier. |journal=Hum. Genet. |volume=93 |issue= 5 |pages= 600–2 |year= 1994 |pmid= 8168843 |doi=
*cite journal | author=Matsuda C, Endo H, Ohta S, Kagawa Y |title=Gene structure of human mitochondrial ATP synthase gamma-subunit. Tissue specificity produced by alternative RNA splicing. |journal=J. Biol. Chem. |volume=268 |issue= 33 |pages= 24950–8 |year= 1993 |pmid= 8227057 |doi=
*cite journal | author=Elston T, Wang H, Oster G |title=Energy transduction in ATP synthase. |journal=Nature |volume=391 |issue= 6666 |pages= 510–3 |year= 1998 |pmid= 9461222 |doi= 10.1038/35185
*cite journal | author=Yasuda R, Noji H, Kinosita K, Yoshida M |title=F1-ATPase is a highly efficient molecular motor that rotates with discrete 120 degree steps. |journal=Cell |volume=93 |issue= 7 |pages= 1117–24 |year= 1998 |pmid= 9657145 |doi=
*cite journal | author=Wang H, Oster G |title=Energy transduction in the F1 motor of ATP synthase. |journal=Nature |volume=396 |issue= 6708 |pages= 279–82 |year= 1998 |pmid= 9834036 |doi= 10.1038/24409
*cite journal | author=Hayakawa M, Sakashita E, Ueno E, "et al." |title=Muscle-specific exonic splicing silencer for exon exclusion in human ATP synthase gamma-subunit pre-mRNA. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 6974–84 |year= 2002 |pmid= 11744705 |doi= 10.1074/jbc.M110138200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cross RL |title=Molecular motors: turning the ATP motor. |journal=Nature |volume=427 |issue= 6973 |pages= 407–8 |year= 2004 |pmid= 14749816 |doi= 10.1038/427407b
*cite journal | author=Itoh H, Takahashi A, Adachi K, "et al." |title=Mechanically driven ATP synthesis by F1-ATPase. |journal=Nature |volume=427 |issue= 6973 |pages= 465–8 |year= 2004 |pmid= 14749837 |doi= 10.1038/nature02212
*cite journal | author=Deloukas P, Earthrowl ME, Grafham DV, "et al." |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Fukumura K, Kato A, Jin Y, "et al." |title=Tissue-specific splicing regulator Fox-1 induces exon skipping by interfering E complex formation on the downstream intron of human F1gamma gene. |journal=Nucleic Acids Res. |volume=35 |issue= 16 |pages= 5303–11 |year= 2007 |pmid= 17686786 |doi= 10.1093/nar/gkm569

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