- KIF5A
Kinesin family member 5A, also known as KIF5A, is a human
gene .cite web | title = Entrez Gene: KIF5A kinesin family member 5A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3798| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10.cite web | title = Entrez Gene: KIF5A kinesin family member 5A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3798| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Fichera M, Lo Giudice M, Falco M, "et al." |title=Evidence of kinesin heavy chain (KIF5A) involvement in pure hereditary spastic paraplegia. |journal=Neurology |volume=63 |issue= 6 |pages= 1108–10 |year= 2005 |pmid= 15452312 |doi=
*cite journal | author=Niclas J, Navone F, Hom-Booher N, Vale RD |title=Cloning and localization of a conventional kinesin motor expressed exclusively in neurons. |journal=Neuron |volume=12 |issue= 5 |pages= 1059–72 |year= 1994 |pmid= 7514426 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Rahman A, Friedman DS, Goldstein LS |title=Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins. |journal=J. Biol. Chem. |volume=273 |issue= 25 |pages= 15395–403 |year= 1998 |pmid= 9624122 |doi=
*cite journal | author=Hamlin PJ, Jones PF, Leek JP, "et al." |title=Assignment of GALGT encoding beta-1, 4N-acetylgalactosaminyl-transferase (GalNAc-T) and KIF5A encoding neuronal kinesin (D12S1889) to human chromosome band 12q13 by assignment to ICI YAC 26EG10 and in situ hybridization. medjph@stjames.leeds.ac.uk. |journal=Cytogenet. Cell Genet. |volume=82 |issue= 3-4 |pages= 267–8 |year= 1999 |pmid= 9858832 |doi=
*cite journal | author=Reid E, Dearlove AM, Rhodes M, Rubinsztein DC |title=A new locus for autosomal dominant "pure" hereditary spastic paraplegia mapping to chromosome 12q13, and evidence for further genetic heterogeneity. |journal=Am. J. Hum. Genet. |volume=65 |issue= 3 |pages= 757–63 |year= 1999 |pmid= 10441583 |doi=
*cite journal | author=Rahman A, Kamal A, Roberts EA, Goldstein LS |title=Defective kinesin heavy chain behavior in mouse kinesin light chain mutants. |journal=J. Cell Biol. |volume=146 |issue= 6 |pages= 1277–88 |year= 1999 |pmid= 10491391 |doi=
*cite journal | author=Kanai Y, Okada Y, Tanaka Y, "et al." |title=KIF5C, a novel neuronal kinesin enriched in motor neurons. |journal=J. Neurosci. |volume=20 |issue= 17 |pages= 6374–84 |year= 2000 |pmid= 10964943 |doi=
*cite journal | author=Setou M, Seog DH, Tanaka Y, "et al." |title=Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. |journal=Nature |volume=417 |issue= 6884 |pages= 83–7 |year= 2002 |pmid= 11986669 |doi= 10.1038/nature743
*cite journal | author=Reid E, Kloos M, Ashley-Koch A, "et al." |title=A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10). |journal=Am. J. Hum. Genet. |volume=71 |issue= 5 |pages= 1189–94 |year= 2003 |pmid= 12355402 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Macioce P, Gambara G, Bernassola M, "et al." |title=Beta-dystrobrevin interacts directly with kinesin heavy chain in brain. |journal=J. Cell. Sci. |volume=116 |issue= Pt 23 |pages= 4847–56 |year= 2004 |pmid= 14600269 |doi= 10.1242/jcs.00805
*cite journal | author=Amit I, Yakir L, Katz M, "et al." |title=Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding. |journal=Genes Dev. |volume=18 |issue= 14 |pages= 1737–52 |year= 2004 |pmid= 15256501 |doi= 10.1101/gad.294904
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Blair MA, Ma S, Hedera P |title=Mutation in KIF5A can also cause adult-onset hereditary spastic paraplegia. |journal=Neurogenetics |volume=7 |issue= 1 |pages= 47–50 |year= 2007 |pmid= 16489470 |doi= 10.1007/s10048-005-0027-8PBB_Controls
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