- BNC1
Basonuclin 1, also known as BNC1, is a human
gene .cite web | title = Entrez Gene: BNC1 basonuclin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=646| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a zinc finger protein present in the basal cell layer of the epidermis and in hair follicles. It is also found in abundance in the germ cells of testis and ovary. This protein is thought to play a regulatory role in keratinocyte proliferation and it may also be a regulator for rRNA transcription. This gene seems to have multiple alternatively spliced transcript variants, but their full-length nature is not known yet. There seems to be evidence of multiple polyadenylation sites for this gene.cite web | title = Entrez Gene: BNC1 basonuclin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=646| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Tseng H |title=Basonuclin, a zinc finger protein associated with epithelial expansion and proliferation. |journal=Front. Biosci. |volume=3 |issue= |pages= D985–8 |year= 1998 |pmid= 9727087 |doi=
*cite journal | author=Tseng H, Green H |title=Basonuclin: a keratinocyte protein with multiple paired zinc fingers. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 21 |pages= 10311–5 |year= 1992 |pmid= 1332044 |doi=
*cite journal | author=Tseng H, Green H |title=Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation. |journal=J. Cell Biol. |volume=126 |issue= 2 |pages= 495–506 |year= 1994 |pmid= 8034748 |doi=
*cite journal | author=Teumer J, Tseng H, Green H |title=The human basonuclin gene. |journal=Gene |volume=188 |issue= 1 |pages= 1–7 |year= 1997 |pmid= 9099851 |doi=
*cite journal | author=Yang Z, Gallicano GI, Yu QC, Fuchs E |title=An unexpected localization of basonuclin in the centrosome, mitochondria, and acrosome of developing spermatids. |journal=J. Cell Biol. |volume=137 |issue= 3 |pages= 657–69 |year= 1997 |pmid= 9151672 |doi=
*cite journal | author=Iuchi S, Green H |title=Nuclear localization of basonuclin in human keratinocytes and the role of phosphorylation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 15 |pages= 7948–53 |year= 1997 |pmid= 9223293 |doi=
*cite journal | author=Mahoney MG, Tang W, Xiang MM, "et al." |title=Translocation of the zinc finger protein basonuclin from the mouse germ cell nucleus to the midpiece of the spermatozoon during spermiogenesis. |journal=Biol. Reprod. |volume=59 |issue= 2 |pages= 388–94 |year= 1998 |pmid= 9687312 |doi=
*cite journal | author=Iuchi S, Green H |title=Basonuclin, a zinc finger protein of keratinocytes and reproductive germ cells, binds to the rRNA gene promoter. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 17 |pages= 9628–32 |year= 1999 |pmid= 10449744 |doi=
*cite journal | author=Tseng H, Biegel JA, Brown RS |title=Basonuclin is associated with the ribosomal RNA genes on human keratinocyte mitotic chromosomes. |journal=J. Cell. Sci. |volume=112 Pt 18 |issue= |pages= 3039–47 |year= 2000 |pmid= 10462520 |doi=
*cite journal | author=Tang W, Tseng H |title=A GC-rich sequence within the 5' untranslated region of human basonuclin mRNA inhibits its translation. |journal=Gene |volume=237 |issue= 1 |pages= 35–44 |year= 1999 |pmid= 10524234 |doi=
*cite journal | author=Iuchi S, Easley K, Matsuzaki K, "et al." |title=Alternative subcellular locations of keratinocyte basonuclin. |journal=Exp. Dermatol. |volume=9 |issue= 3 |pages= 178–84 |year= 2000 |pmid= 10839715 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Chen L, Willis SN, Wei A, "et al." |title=Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. |journal=Mol. Cell |volume=17 |issue= 3 |pages= 393–403 |year= 2005 |pmid= 15694340 |doi= 10.1016/j.molcel.2004.12.030
*cite journal | author=Vanhoutteghem A, Djian P |title=Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 33 |pages= 12423–8 |year= 2006 |pmid= 16891417 |doi= 10.1073/pnas.0605086103PBB_Controls
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