NDRG4

NDRG4
NDRG family member 4
Identifiers
Symbols NDRG4; DKFZp686I1615; FLJ30586; FLJ42011; KIAA1180; MGC19632; SMAP-8
External IDs MGI2384590 HomoloGene23228 GeneCards: NDRG4 Gene
RNA expression pattern
PBB GE NDRG4 209159 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 65009 234593
Ensembl ENSG00000103034 ENSMUSG00000036564
UniProt Q9ULP0 Q8BTG7
RefSeq (mRNA) NM_001130487.1 NM_145602
RefSeq (protein) NP_001123959.1 NP_663577
Location (UCSC) Chr 16:
58.5 – 58.55 Mb
Chr 8:
98.2 – 98.24 Mb
PubMed search [1] [2]

Protein NDRG4 is a protein that in humans is encoded by the NDRG4 gene.[1][2][3]

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[3]

References

  1. ^ Zhou RH, Kokame K, Tsukamoto Y, Yutani C, Kato H, Miyata T (May 2001). "Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart". Genomics 73 (1): 86–97. doi:10.1006/geno.2000.6496. PMID 11352569. 
  2. ^ Hongo S, Watanabe T, Takahashi K, Miyazaki A (Apr 2006). "Ndrg4 enhances NGF-induced ERK activation uncoupled with Elk-1 activation". J Cell Biochem 98 (1): 185–93. doi:10.1002/jcb.20763. PMID 16408304. 
  3. ^ a b "Entrez Gene: NDRG4 NDRG family member 4". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=65009. 

Further reading



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Look at other dictionaries:

  • NDRG2 — NDRG family member 2 Identifiers Symbols NDRG2; DKFZp781G1938; FLJ25522; KIAA1248; SYLD External IDs …   Wikipedia

  • NDRG1 — N myc downstream regulated 1 Identifiers Symbols NDRG1; CAP43; CMT4D; DRG1; GC4; HMSNL; NDR1; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5 External IDs …   Wikipedia

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