PGDS

Prostaglandin D2 synthase, hematopoietic, also known as PGDS, is a human gene.cite web | title = Entrez Gene: PGDS prostaglandin D2 synthase, hematopoietic| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27306| accessdate = ]

PBB_Summary
section_title =
summary_text = Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.cite web | title = Entrez Gene: PGDS prostaglandin D2 synthase, hematopoietic| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27306| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kanaoka Y, Urade Y |title=Hematopoietic prostaglandin D synthase. |journal=Prostaglandins Leukot. Essent. Fatty Acids |volume=69 |issue= 2-3 |pages= 163–7 |year= 2004 |pmid= 12895599 |doi=
*cite journal | author=Kanaoka Y, Ago H, Inagaki E, "et al." |title=Cloning and crystal structure of hematopoietic prostaglandin D synthase. |journal=Cell |volume=90 |issue= 6 |pages= 1085–95 |year= 1997 |pmid= 9323136 |doi=
*cite journal | author=Mahmud I, Ueda N, Yamaguchi H, "et al." |title=Prostaglandin D synthase in human megakaryoblastic cells. |journal=J. Biol. Chem. |volume=272 |issue= 45 |pages= 28263–6 |year= 1997 |pmid= 9353279 |doi=
*cite journal | author=Suzuki T, Watanabe K, Kanaoka Y, "et al." |title=Induction of hematopoietic prostaglandin D synthase in human megakaryocytic cells by phorbol ester. |journal=Biochem. Biophys. Res. Commun. |volume=241 |issue= 2 |pages= 288–93 |year= 1998 |pmid= 9425264 |doi= 10.1006/bbrc.1997.7803
*cite journal | author=Tokugawa Y, Kunishige I, Kubota Y, "et al." |title=Lipocalin-type prostaglandin D synthase in human male reproductive organs and seminal plasma. |journal=Biol. Reprod. |volume=58 |issue= 2 |pages= 600–7 |year= 1998 |pmid= 9475419 |doi=
*cite journal | author=Pinzar E, Kanaoka Y, Inui T, "et al." |title=Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 9 |pages= 4903–7 |year= 2000 |pmid= 10781097 |doi= 10.1073/pnas.090093997
*cite journal | author=Kanaoka Y, Fujimori K, Kikuno R, "et al." |title=Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthase. Conservation of the ancestral genomic structure of sigma-class glutathione S-transferase. |journal=Eur. J. Biochem. |volume=267 |issue= 11 |pages= 3315–22 |year= 2000 |pmid= 10824118 |doi=
*cite journal | author=Fujimori K, Kanaoka Y, Sakaguchi Y, Urade Y |title=Transcriptional activation of the human hematopoietic prostaglandin D synthase gene in megakaryoblastic cells. Roles of the oct-1 element in the 5'-flanking region and the AP-2 element in the untranslated exon 1. |journal=J. Biol. Chem. |volume=275 |issue= 51 |pages= 40511–6 |year= 2001 |pmid= 10998423 |doi= 10.1074/jbc.M007688200
*cite journal | author=Sui D, Wilson JE |title=Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type prostaglandin D synthase, and granulin precursor with the N-terminal half of type III hexokinase. |journal=Arch. Biochem. Biophys. |volume=382 |issue= 2 |pages= 262–74 |year= 2000 |pmid= 11068878 |doi= 10.1006/abbi.2000.2019
*cite journal | author=Jowsey IR, Thomson AM, Flanagan JU, "et al." |title=Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases. |journal=Biochem. J. |volume=359 |issue= Pt 3 |pages= 507–16 |year= 2001 |pmid= 11672424 |doi=
*cite journal | author=Noguchi E, Shibasaki M, Kamioka M, "et al." |title=New polymorphisms of haematopoietic prostaglandin D synthase and human prostanoid DP receptor genes. |journal=Clin. Exp. Allergy |volume=32 |issue= 1 |pages= 93–6 |year= 2002 |pmid= 12002745 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Inoue T, Irikura D, Okazaki N, "et al." |title=Mechanism of metal activation of human hematopoietic prostaglandin D synthase. |journal=Nat. Struct. Biol. |volume=10 |issue= 4 |pages= 291–6 |year= 2003 |pmid= 12627223 |doi= 10.1038/nsb907
*cite journal | author=Ando M, Murakami Y, Kojima F, "et al." |title=Retrovirally introduced prostaglandin D2 synthase suppresses lung injury induced by bleomycin. |journal=Am. J. Respir. Cell Mol. Biol. |volume=28 |issue= 5 |pages= 582–91 |year= 2003 |pmid= 12707014 |doi= 10.1165/rcmb.2002-0162OC
*cite journal | author=Inoue T, Okano Y, Kado Y, "et al." |title=First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase. |journal=J. Biochem. |volume=135 |issue= 3 |pages= 279–83 |year= 2005 |pmid= 15113825 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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