TNFRSF17

Tumor necrosis factor receptor superfamily, member 17, also known as TNFRSF17, is a human gene.cite web | title = Entrez Gene: TNFRSF17 tumor necrosis factor receptor superfamily, member 17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=608| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.cite web | title = Entrez Gene: TNFRSF17 tumor necrosis factor receptor superfamily, member 17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=608| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Treml LS, Crowley JE, Cancro MP |title=BLyS receptor signatures resolve homeostatically independent compartments among naïve and antigen-experienced B cells. |journal=Semin. Immunol. |volume=18 |issue= 5 |pages= 297–304 |year= 2007 |pmid= 16919470 |doi= 10.1016/j.smim.2006.07.001
*cite journal | author=Mackay F, Leung H |title=The role of the BAFF/APRIL system on T cell function. |journal=Semin. Immunol. |volume=18 |issue= 5 |pages= 284–9 |year= 2007 |pmid= 16931039 |doi= 10.1016/j.smim.2006.04.005
*cite journal | author=Laâbi Y, Gras MP, Carbonnel F, "et al." |title=A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma. |journal=EMBO J. |volume=11 |issue= 11 |pages= 3897–904 |year= 1992 |pmid= 1396583 |doi=
*cite journal | author=Laabi Y, Gras MP, Brouet JC, "et al." |title=The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed. |journal=Nucleic Acids Res. |volume=22 |issue= 7 |pages= 1147–54 |year= 1994 |pmid= 8165126 |doi=
*cite journal | author=Gras MP, Laâbi Y, Linares-Cruz G, "et al." |title=BC
journal=Int. Immunol. |volume=7 |issue= 7 |pages= 1093–106 |year= 1996 |pmid= 8527407 |doi=
*cite journal | author=Loftus BJ, Kim UJ, Sneddon VP, "et al." |title=Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. |journal=Genomics |volume=60 |issue= 3 |pages= 295–308 |year= 1999 |pmid= 10493829 |doi= 10.1006/geno.1999.5927
*cite journal | author=Gross JA, Johnston J, Mudri S, "et al." |title=TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. |journal=Nature |volume=404 |issue= 6781 |pages= 995–9 |year= 2000 |pmid= 10801128 |doi= 10.1038/35010115
*cite journal | author=Hatzoglou A, Roussel J, Bourgeade MF, "et al." |title=TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase. |journal=J. Immunol. |volume=165 |issue= 3 |pages= 1322–30 |year= 2000 |pmid= 10903733 |doi=
*cite journal | author=Shu HB, Johnson H |title=B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 16 |pages= 9156–61 |year= 2000 |pmid= 10908663 |doi= 10.1073/pnas.160213497
*cite journal | author=Yu G, Boone T, Delaney J, "et al." |title=APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. |journal=Nat. Immunol. |volume=1 |issue= 3 |pages= 252–6 |year= 2001 |pmid= 10973284 |doi= 10.1038/79802
*cite journal | author=Kawasaki A, Tsuchiya N, Fukazawa T, "et al." |title=Presence of four major haplotypes in human BCMA gene: lack of association with systemic lupus erythematosus and rheumatoid arthritis. |journal=Genes Immun. |volume=2 |issue= 5 |pages= 276–9 |year= 2001 |pmid= 11528522 |doi= 10.1038/sj.gene.6363770
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Novak AJ, Darce JR, Arendt BK, "et al." |title=Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. |journal=Blood |volume=103 |issue= 2 |pages= 689–94 |year= 2004 |pmid= 14512299 |doi= 10.1182/blood-2003-06-2043
*cite journal | author=Hymowitz SG, Patel DR, Wallweber HJ, "et al." |title=Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. |journal=J. Biol. Chem. |volume=280 |issue= 8 |pages= 7218–27 |year= 2005 |pmid= 15542592 |doi= 10.1074/jbc.M411714200
*cite journal | author=Bellucci R, Alyea EP, Chiaretti S, "et al." |title=Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor. |journal=Blood |volume=105 |issue= 10 |pages= 3945–50 |year= 2005 |pmid= 15692072 |doi= 10.1182/blood-2004-11-4463
*cite journal | author=Hendriks J, Planelles L, de Jong-Odding J, "et al." |title=Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation. |journal=Cell Death Differ. |volume=12 |issue= 6 |pages= 637–48 |year= 2005 |pmid= 15846369 |doi= 10.1038/sj.cdd.4401647
*cite journal | author=Chiu A, Xu W, He B, "et al." |title=Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL. |journal=Blood |volume=109 |issue= 2 |pages= 729–39 |year= 2007 |pmid= 16960154 |doi= 10.1182/blood-2006-04-015958
*cite journal | author=Smirnova AS, Andrade-Oliveira V, Gerbase-Delima M |title=Identification of new splice variants of the genes BAFF and BCMA. |journal= |volume=45 |issue= 4 |pages= 1179–1183 |year= |pmid= 17825416 |doi= 10.1016/j.molimm.2007.07.028

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