KLK13

Kallikrein-related peptidase 13, also known as KLK13, is a human gene.cite web | title = Entrez Gene: KLK13 kallikrein-related peptidase 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26085| accessdate = ]

PBB_Summary
section_title =
summary_text = Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined.cite web | title = Entrez Gene: KLK13 kallikrein-related peptidase 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26085| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Diamandis EP, Yousef GM, Luo LY, "et al." |title=The new human kallikrein gene family: implications in carcinogenesis. |journal=Trends Endocrinol. Metab. |volume=11 |issue= 2 |pages= 54–60 |year= 2001 |pmid= 10675891 |doi=
*cite journal | author=Yousef GM, Chang A, Diamandis EP |title=Identification and characterization of KLK-L4, a new kallikrein-like gene that appears to be down-regulated in breast cancer tissues. |journal=J. Biol. Chem. |volume=275 |issue= 16 |pages= 11891–8 |year= 2000 |pmid= 10766816 |doi=
*cite journal | author=Yousef GM, Chang A, Scorilas A, Diamandis EP |title=Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 1 |pages= 125–33 |year= 2000 |pmid= 11006094 |doi= 10.1006/bbrc.2000.3448
*cite journal | author=Gan L, Lee I, Smith R, "et al." |title=Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. |journal=Gene |volume=257 |issue= 1 |pages= 119–30 |year= 2001 |pmid= 11054574 |doi=
*cite journal | author=Chang A, Yousef GM, Jung K, "et al." |title=Identification and molecular characterization of five novel kallikrein gene 13 (KLK13; KLK-L4) splice variants: differential expression in the human testis and testicular cancer. |journal=Anticancer Res. |volume=21 |issue= 5 |pages= 3147–52 |year= 2002 |pmid= 11848466 |doi=
*cite journal | author=Chang A, Yousef GM, Scorilas A, "et al." |title=Human kallikrein gene 13 (KLK13) expression by quantitative RT-PCR: an independent indicator of favourable prognosis in breast cancer. |journal=Br. J. Cancer |volume=86 |issue= 9 |pages= 1457–64 |year= 2002 |pmid= 11986781 |doi= 10.1038/sj.bjc.6600283
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Petraki CD, Karavana VN, Diamandis EP |title=Human kallikrein 13 expression in normal tissues: an immunohistochemical study. |journal=J. Histochem. Cytochem. |volume=51 |issue= 4 |pages= 493–501 |year= 2003 |pmid= 12642628 |doi=
*cite journal | author=Komatsu N, Takata M, Otsuki N, "et al." |title=Expression and localization of tissue kallikrein mRNAs in human epidermis and appendages. |journal=J. Invest. Dermatol. |volume=121 |issue= 3 |pages= 542–9 |year= 2003 |pmid= 12925213 |doi= 10.1046/j.1523-1747.2003.12363.x
*cite journal | author=Petraki CD, Gregorakis AK, Papanastasiou PA, "et al." |title=Immunohistochemical localization of human kallikreins 6, 10 and 13 in benign and malignant prostatic tissues. |journal=Prostate Cancer Prostatic Dis. |volume=6 |issue= 3 |pages= 223–7 |year= 2004 |pmid= 12970725 |doi= 10.1038/sj.pcan.4500674
*cite journal | author=Kapadia C, Yousef GM, Mellati AA, "et al." |title=Complex formation between human kallikrein 13 and serum protease inhibitors. |journal=Clin. Chim. Acta |volume=339 |issue= 1-2 |pages= 157–67 |year= 2004 |pmid= 14687906 |doi=
*cite journal | author=Grimwood J, Gordon LA, Olsen A, "et al." |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399
*cite journal | author=Kapadia C, Ghosh MC, Grass L, Diamandis EP |title=Human kallikrein 13 involvement in extracellular matrix degradation. |journal=Biochem. Biophys. Res. Commun. |volume=323 |issue= 3 |pages= 1084–90 |year= 2004 |pmid= 15381110 |doi= 10.1016/j.bbrc.2004.08.206
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author= |title=Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005. |journal=Biol. Chem. |volume=387 |issue= 6 |pages= 635–824 |year= 2006 |pmid= 16800723 |doi= 10.1515/BC.2006.081
*cite journal | author=Lundwall A, Band V, Blaber M, "et al." |title=A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. |journal=Biol. Chem. |volume=387 |issue= 6 |pages= 637–41 |year= 2006 |pmid= 16800724 |doi= 10.1515/BC.2006.082
*cite journal | author=Darling MR, Jackson-Boeters L, Daley TD, Diamandis EP |title=Human kallikrein 13 expression in salivary gland tumors. |journal=Int. J. Biol. Markers |volume=21 |issue= 2 |pages= 106–10 |year= 2006 |pmid= 16847813 |doi=

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