- RPL14
Ribosomal protein L14, also known as RPL14, is a human
gene .cite web | title = Entrez Gene: RPL14 ribosomal protein L14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9045| accessdate = ]PBB_Summary
section_title =
summary_text = Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.cite web | title = Entrez Gene: RPL14 ribosomal protein L14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9045| accessdate = ]References
Further reading
PBB_Further_reading
citations =
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*cite journal | author=Li SH, McInnis MG, Margolis RL, "et al." |title=Novel triplet repeat containing genes in human brain: cloning, expression, and length polymorphisms. |journal=Genomics |volume=16 |issue= 3 |pages= 572–9 |year= 1993 |pmid= 8325628 |doi= 10.1006/geno.1993.1232
*cite journal | author=Aoki M, Koranyi L, Riggs AC, "et al." |title=Identification of trinucleotide repeat-containing genes in human pancreatic islets. |journal=Diabetes |volume=45 |issue= 2 |pages= 157–64 |year= 1996 |pmid= 8549859 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Reddy PH, Stockburger E, Gillevet P, Tagle DA |title=Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method. |journal=Genomics |volume=46 |issue= 2 |pages= 174–82 |year= 1998 |pmid= 9417904 |doi= 10.1006/geno.1997.5044
*cite journal | author=Tanaka M, Tanaka T, Harata M, "et al." |title=Triplet repeat-containing ribosomal protein L14 gene in immortalized human endothelial cell line (t-HUE4). |journal=Biochem. Biophys. Res. Commun. |volume=243 |issue= 2 |pages= 531–7 |year= 1998 |pmid= 9480843 |doi= 10.1006/bbrc.1998.8125
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*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Odintsova TI, Müller EC, Ivanov AV, "et al." |title=Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. |journal=J. Protein Chem. |volume=22 |issue= 3 |pages= 249–58 |year= 2004 |pmid= 12962325 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026PBB_Controls
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