BTAF1

BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae), also known as BTAF1, is a human gene.cite web | title = Entrez Gene: BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9044| accessdate = ]

PBB_Summary
section_title =
summary_text = Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP; MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B; MIM 604912), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity. [supplied by OMIM] cite web | title = Entrez Gene: BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9044| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Zhou Q, Sharp PA |title=Novel mechanism and factor for regulation by HIV-1 Tat. |journal=EMBO J. |volume=14 |issue= 2 |pages= 321–8 |year= 1995 |pmid= 7835343 |doi=
*cite journal | author=Parada CA, Yoon JB, Roeder RG |title=A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro. |journal=J. Biol. Chem. |volume=270 |issue= 5 |pages= 2274–83 |year= 1995 |pmid= 7836461 |doi=
*cite journal | author=Ou SH, Garcia-Martínez LF, Paulssen EJ, Gaynor RB |title=Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function. |journal=J. Virol. |volume=68 |issue= 11 |pages= 7188–99 |year= 1994 |pmid= 7933101 |doi=
*cite journal | author=Kashanchi F, Piras G, Radonovich MF, "et al." |title=Direct interaction of human TFIID with the HIV-1 transactivator tat. |journal=Nature |volume=367 |issue= 6460 |pages= 295–9 |year= 1994 |pmid= 8121496 |doi= 10.1038/367295a0
*cite journal | author=Wang Z, Morris GF, Rice AP, "et al." |title=Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro. |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=12 |issue= 2 |pages= 128–38 |year= 1996 |pmid= 8680883 |doi=
*cite journal | author=Pendergrast PS, Morrison D, Tansey WP, Hernandez N |title=Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly. |journal=J. Virol. |volume=70 |issue= 8 |pages= 5025–34 |year= 1996 |pmid= 8764009 |doi=
*cite journal | author=Kashanchi F, Khleif SN, Duvall JF, "et al." |title=Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex. |journal=J. Virol. |volume=70 |issue= 8 |pages= 5503–10 |year= 1996 |pmid= 8764062 |doi=
*cite journal | author=Zhou Q, Sharp PA |title=Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat. |journal=Science |volume=274 |issue= 5287 |pages= 605–10 |year= 1996 |pmid= 8849451 |doi=
*cite journal | author=García-Martínez LF, Ivanov D, Gaynor RB |title=Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes. |journal=J. Biol. Chem. |volume=272 |issue= 11 |pages= 6951–8 |year= 1997 |pmid= 9054383 |doi=
*cite journal | author=Scully R, Anderson SF, Chao DM, "et al." |title=BRCA1 is a component of the RNA polymerase II holoenzyme. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 11 |pages= 5605–10 |year= 1997 |pmid= 9159119 |doi=
*cite journal | author=van der Knaap JA, Borst JW, van der Vliet PC, "et al." |title=Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 22 |pages= 11827–32 |year= 1997 |pmid= 9342322 |doi=
*cite journal | author=Chicca JJ, Auble DT, Pugh BF |title=Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1. |journal=Mol. Cell. Biol. |volume=18 |issue= 3 |pages= 1701–10 |year= 1998 |pmid= 9488487 |doi=
*cite journal | author=Van Der Knaap JA, Van Den Boom V, Kuipers J, "et al." |title=The gene for human TATA-binding-protein-associated factor (TAFII) 170: structure, promoter and chromosomal localization. |journal=Biochem. J. |volume=345 Pt 3 |issue= |pages= 521–7 |year= 2000 |pmid= 10642510 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wadhwa R, Yaguchi T, Hasan MK, "et al." |title=Mortalin-MPD (mevalonate pyrophosphate decarboxylase) interactions and their role in control of cellular proliferation. |journal=Biochem. Biophys. Res. Commun. |volume=302 |issue= 4 |pages= 735–42 |year= 2003 |pmid= 12646231 |doi=
*cite journal | author=Pereira LA, Klejman MP, Ruhlmann C, "et al." |title=Molecular architecture of the basal transcription factor B-TFIID. |journal=J. Biol. Chem. |volume=279 |issue= 21 |pages= 21802–7 |year= 2004 |pmid= 14988402 |doi= 10.1074/jbc.M313519200
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Klejman MP, Pereira LA, van Zeeburg HJ, "et al." |title=NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein. |journal=Mol. Cell. Biol. |volume=24 |issue= 22 |pages= 10072–82 |year= 2004 |pmid= 15509807 |doi= 10.1128/MCB.24.22.10072-10082.2004
*cite journal | author=Grob P, Cruse MJ, Inouye C, "et al." |title=Cryo-electron microscopy studies of human TFIID: conformational breathing in the integration of gene regulatory cues. |journal=Structure |volume=14 |issue= 3 |pages= 511–20 |year= 2006 |pmid= 16531235 |doi= 10.1016/j.str.2005.11.020

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