SCO1

SCO cytochrome oxidase deficient homolog 1 (yeast), also known as SCO1, is a human gene.cite web | title = Entrez Gene: SCO1 SCO cytochrome oxidase deficient homolog 1 (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6341| accessdate = ]

PBB_Summary
section_title =
summary_text = Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene.cite web | title = Entrez Gene: SCO1 SCO cytochrome oxidase deficient homolog 1 (yeast)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6341| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Shoubridge EA |title=Cytochrome c oxidase deficiency. |journal=Am. J. Med. Genet. |volume=106 |issue= 1 |pages= 46–52 |year= 2001 |pmid= 11579424 |doi= 10.1002/ajmg.1378
*cite journal | author=Schulze M, Rödel G |title=Accumulation of the cytochrome c oxidase subunits I and II in yeast requires a mitochondrial membrane-associated protein, encoded by the nuclear SCO1 gene. |journal=Mol. Gen. Genet. |volume=216 |issue= 1 |pages= 37–43 |year= 1989 |pmid= 2543907 |doi=
*cite journal | author=Schulze M, Rödel G |title=SCO1, a yeast nuclear gene essential for accumulation of mitochondrial cytochrome c oxidase subunit II. |journal=Mol. Gen. Genet. |volume=211 |issue= 3 |pages= 492–8 |year= 1988 |pmid= 2835635 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Petruzzella V, Tiranti V, Fernandez P, "et al." |title=Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain. |journal=Genomics |volume=54 |issue= 3 |pages= 494–504 |year= 1999 |pmid= 9878253 |doi= 10.1006/geno.1998.5580
*cite journal | author=Paret C, Ostermann K, Krause-Buchholz U, "et al." |title=Human members of the SCO1 gene family: complementation analysis in yeast and intracellular localization. |journal=FEBS Lett. |volume=447 |issue= 1 |pages= 65–70 |year= 1999 |pmid= 10218584 |doi=
*cite journal | author=Papadopoulou LC, Sue CM, Davidson MM, "et al." |title=Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene. |journal=Nat. Genet. |volume=23 |issue= 3 |pages= 333–7 |year= 1999 |pmid= 10545952 |doi= 10.1038/15513
*cite journal | author=Valnot I, Osmond S, Gigarel N, "et al." |title=Mutations of the SCO1 gene in mitochondrial cytochrome c oxidase deficiency with neonatal-onset hepatic failure and encephalopathy. |journal=Am. J. Hum. Genet. |volume=67 |issue= 5 |pages= 1104–9 |year= 2000 |pmid= 11013136 |doi=
*cite journal | author=Horvath R, Lochmüller H, Stucka R, "et al." |title=Characterization of human SCO1 and COX17 genes in mitochondrial cytochrome-c-oxidase deficiency. |journal=Biochem. Biophys. Res. Commun. |volume=276 |issue= 2 |pages= 530–3 |year= 2000 |pmid= 11027508 |doi= 10.1006/bbrc.2000.3495
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Leary SC, Kaufman BA, Pellecchia G, "et al." |title=Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase. |journal=Hum. Mol. Genet. |volume=13 |issue= 17 |pages= 1839–48 |year= 2005 |pmid= 15229189 |doi= 10.1093/hmg/ddh197
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Williams JC, Sue C, Banting GS, "et al." |title=Crystal structure of human SCO1: implications for redox signaling by a mitochondrial cytochrome c oxidase "assembly" protein. |journal=J. Biol. Chem. |volume=280 |issue= 15 |pages= 15202–11 |year= 2005 |pmid= 15659396 |doi= 10.1074/jbc.M410705200
*cite journal | author=Horng YC, Leary SC, Cobine PA, "et al." |title=Human Sco1 and Sco2 function as copper-binding proteins. |journal=J. Biol. Chem. |volume=280 |issue= 40 |pages= 34113–22 |year= 2005 |pmid= 16091356 |doi= 10.1074/jbc.M506801200
*cite journal | author=Cobine PA, Pierrel F, Leary SC, "et al." |title=The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding. |journal=J. Biol. Chem. |volume=281 |issue= 18 |pages= 12270–6 |year= 2006 |pmid= 16520371 |doi= 10.1074/jbc.M600496200
*cite journal | author=Banci L, Bertini I, Calderone V, "et al." |title=A hint for the function of human Sco1 from different structures. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 23 |pages= 8595–600 |year= 2006 |pmid= 16735468 |doi= 10.1073/pnas.0601375103
*cite journal | author=Leary SC, Cobine PA, Kaufman BA, "et al." |title=The human cytochrome c oxidase assembly factors SCO1 and SCO2 have regulatory roles in the maintenance of cellular copper homeostasis. |journal=Cell Metab. |volume=5 |issue= 1 |pages= 9–20 |year= 2007 |pmid= 17189203 |doi= 10.1016/j.cmet.2006.12.001

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes