MYL4

MYL4

Myosin, light chain 4, alkali; atrial, embryonic, also known as MYL4, is a human gene.cite web | title = Entrez Gene: MYL4 myosin, light chain 4, alkali; atrial, embryonic| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4635| accessdate = ]

PBB_Summary
section_title =
summary_text = Myosin is a hexameric ATPase cellular motor protein. It is composed of two myosin heavy chains, two nonphosphorylatable myosin alkali light chains, and two phosphorylatable myosin regulatory light chains. This gene encodes a myosin alkali light chain that is found in embryonic muscle and adult atria. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: MYL4 myosin, light chain 4, alkali; atrial, embryonic| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4635| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rotter M, Zimmerman K, Poustka A, "et al." |title=The human embryonic myosin alkali light chain gene: use of alternative promoters and 3' non-coding regions. |journal=Nucleic Acids Res. |volume=19 |issue= 7 |pages= 1497–504 |year= 1991 |pmid= 2027757 |doi=
*cite journal | author=Seharaseyon J, Bober E, Hsieh CL, "et al." |title=Human embryonic/atrial myosin alkali light chain gene: characterization, sequence, and chromosomal location. |journal=Genomics |volume=7 |issue= 2 |pages= 289–93 |year= 1990 |pmid= 2129532 |doi=
*cite journal | author=Zimmermann K, Kautz S, Hajdu G, "et al." |title=Heterogenic mRNAs with an identical protein-coding region of the human embryonic myosin alkali light chain in skeletal muscle cells. |journal=J. Mol. Biol. |volume=211 |issue= 3 |pages= 505–13 |year= 1990 |pmid= 2308163 |doi=
*cite journal | author=Seidel U, Bober E, Winter B, "et al." |title=Alkali myosin light chains in man are encoded by a multigene family that includes the adult skeletal muscle, the embryonic or atrial, and nonsarcomeric isoforms. |journal=Gene |volume=66 |issue= 1 |pages= 135–46 |year= 1988 |pmid= 2458299 |doi=
*cite journal | author=Arnold HH, Lohse P, Seidel U, Bober E |title=A novel human myosin alkali light chain is developmentally regulated. Expression in fetal cardiac and skeletal muscle and in adult atria. |journal=Eur. J. Biochem. |volume=178 |issue= 1 |pages= 53–60 |year= 1989 |pmid= 2849544 |doi=
*cite journal | author=Kurabayashi M, Komuro I, Tsuchimochi H, "et al." |title=Molecular cloning and characterization of human atrial and ventricular myosin alkali light chain cDNA clones. |journal=J. Biol. Chem. |volume=263 |issue= 27 |pages= 13930–6 |year= 1988 |pmid= 3417683 |doi=
*cite journal | author=Strohman RC, Micou-Eastwood J, Glass CA, Matsuda R |title=Human fetal muscle and cultured myotubes derived from it contain a fetal-specific myosin light chain. |journal=Science |volume=221 |issue= 4614 |pages= 955–7 |year= 1983 |pmid= 6879193 |doi=
*cite journal | author=Timson DJ, Trayer IP |title=The rôle of the proline-rich region in A1-type myosin essential light chains: implications for information transmission in the actomyosin complex. |journal=FEBS Lett. |volume=400 |issue= 1 |pages= 31–6 |year= 1997 |pmid= 9000508 |doi=
*cite journal | author=Timson DJ, Trayer HR, Trayer IP |title=The N-terminus of A1-type myosin essential light chains binds actin and modulates myosin motor function. |journal=Eur. J. Biochem. |volume=255 |issue= 3 |pages= 654–62 |year= 1998 |pmid= 9738905 |doi=
*cite journal | author=Timson DJ, Trayer HR, Smith KJ, Trayer IP |title=Size and charge requirements for kinetic modulation and actin binding by alkali 1-type myosin essential light chains. |journal=J. Biol. Chem. |volume=274 |issue= 26 |pages= 18271–7 |year= 1999 |pmid= 10373429 |doi=
*cite journal | author=Morano I |title=Tuning the human heart molecular motors by myosin light chains. |journal=J. Mol. Med. |volume=77 |issue= 7 |pages= 544–55 |year= 1999 |pmid= 10494800 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Arrell DK, Neverova I, Fraser H, "et al." |title=Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1. |journal=Circ. Res. |volume=89 |issue= 6 |pages= 480–7 |year= 2001 |pmid= 11557734 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Abdelaziz AI, Pagel I, Schlegel WP, "et al." |title=Human atrial myosin light chain 1 expression attenuates heart failure. |journal=Adv. Exp. Med. Biol. |volume=565 |issue= |pages= 283–92; discussion 92, 405–15 |year= 2006 |pmid= 16106982 |doi=
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139

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