DDX6

DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6

PDB rendering based on 1vec.
Identifiers
Symbols DDX6; FLJ36338; HLR2; P54; RCK
External IDs OMIM600326 MGI104976 HomoloGene3238 GeneCards: DDX6 Gene
EC number 3.6.4.13
RNA expression pattern
PBB GE DDX6 204909 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1656 13209
Ensembl ENSG00000110367 ENSMUSG00000032097
UniProt P26196 O54979
RefSeq (mRNA) NM_004397 NM_007841
RefSeq (protein) NP_004388 NP_031867
Location (UCSC) Chr 11:
118.62 – 118.66 Mb
Chr 9:
44.41 – 44.45 Mb
PubMed search [1] [2]

Probable ATP-dependent RNA helicase DDX6 is an enzyme that in humans is encoded by the DDX6 gene.[1][2]

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein. It may contribute to the cell proliferation and carcinogenesis.[2]

References

Further reading


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