EIF4B

EIF4B

Eukaryotic translation initiation factor 4B, also known as EIF4B, is a human gene.cite web | title = Entrez Gene: EIF4B eukaryotic translation initiation factor 4B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1975| accessdate = ]

PBB_Summary
section_title =
summary_text =

References

External links

* [http://www.nature.com/nrmicro/journal/v5/n1/box/nrmicro1558_BX1.html Cap-dependent translation initiation] from Nature Reviews Microbiology. A good image and overview of the function of initiation factors

Further reading

PBB_Further_reading
citations =
*cite journal | author=van Heugten HA, Kasperaitis MA, Thomas AA, Voorma HO |title=Evidence that eukaryotic initiation factor (eIF) 2 is a cap-binding protein that stimulates cap recognition by eIF-4B and eIF-4F. |journal=J. Biol. Chem. |volume=266 |issue= 11 |pages= 7279–84 |year= 1991 |pmid= 2016328 |doi=
*cite journal | author=Milburn SC, Hershey JW, Davies MV, "et al." |title=Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif. |journal=EMBO J. |volume=9 |issue= 9 |pages= 2783–90 |year= 1990 |pmid= 2390971 |doi=
*cite journal | author=Howe JG, Hershey JW |title=Translational initiation factor and ribosome association with the cytoskeletal framework fraction from HeLa cells. |journal=Cell |volume=37 |issue= 1 |pages= 85–93 |year= 1984 |pmid= 6722878 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Méthot N, Pause A, Hershey JW, Sonenberg N |title=The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence. |journal=Mol. Cell. Biol. |volume=14 |issue= 4 |pages= 2307–16 |year= 1994 |pmid= 8139536 |doi=
*cite journal | author=Naranda T, Strong WB, Menaya J, "et al." |title=Two structural domains of initiation factor eIF-4B are involved in binding to RNA. |journal=J. Biol. Chem. |volume=269 |issue= 20 |pages= 14465–72 |year= 1994 |pmid= 8182051 |doi=
*cite journal | author=Méthot N, Song MS, Sonenberg N |title=A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3. |journal=Mol. Cell. Biol. |volume=16 |issue= 10 |pages= 5328–34 |year= 1996 |pmid= 8816444 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Richter NJ, Rogers GW, Hensold JO, Merrick WC |title=Further biochemical and kinetic characterization of human eukaryotic initiation factor 4H. |journal=J. Biol. Chem. |volume=274 |issue= 50 |pages= 35415–24 |year= 2000 |pmid= 10585411 |doi=
*cite journal | author=Bushell M, Wood W, Clemens MJ, Morley SJ |title=Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis. |journal=Eur. J. Biochem. |volume=267 |issue= 4 |pages= 1083–91 |year= 2000 |pmid= 10672017 |doi=
*cite journal | author=Bushell M, Wood W, Carpenter G, "et al." |title=Disruption of the interaction of mammalian protein synthesis eukaryotic initiation factor 4B with the poly(A)-binding protein by caspase- and viral protease-mediated cleavages. |journal=J. Biol. Chem. |volume=276 |issue= 26 |pages= 23922–8 |year= 2001 |pmid= 11274152 |doi= 10.1074/jbc.M100384200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Fleming K, Ghuman J, Yuan X, "et al." |title=Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B. |journal=Biochemistry |volume=42 |issue= 30 |pages= 8966–75 |year= 2003 |pmid= 12885229 |doi= 10.1021/bi034506g
*cite journal | author=Raught B, Peiretti F, Gingras AC, "et al." |title=Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. |journal=EMBO J. |volume=23 |issue= 8 |pages= 1761–9 |year= 2005 |pmid= 15071500 |doi= 10.1038/sj.emboj.7600193
*cite journal | author=Doepker RC, Hsu WL, Saffran HA, Smiley JR |title=Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4H. |journal=J. Virol. |volume=78 |issue= 9 |pages= 4684–99 |year= 2004 |pmid= 15078951 |doi=
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Shahbazian D, Roux PP, Mieulet V, "et al." |title=The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. |journal=EMBO J. |volume=25 |issue= 12 |pages= 2781–91 |year= 2006 |pmid= 16763566 |doi= 10.1038/sj.emboj.7601166
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • Eukaryotic initiation factor — Eukaryotic initiation factors are proteins used in eukaryotic translation. There exist many more eukaryotic initiation factors (eIF) than prokaryotic initiation factors due to greater biological complexity. Processes eIF is involved in include:… …   Wikipedia

  • EIF4H — Eukaryotic translation initiation factor 4H, also known as EIF4H, is a human gene.cite web | title = Entrez Gene: EIF4H eukaryotic translation initiation factor 4H| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… …   Wikipedia

  • Acide ribonucléique messager — Pour les articles homonymes, voir messager. Synthèse et maturation de l ARN messager dans une cellule eucaryote L acide ribonucléique messager, ARN messager ou ARNm est une copie transitoire d une portion de l …   Wikipédia en Français

  • IRES — Un IRES, (Internal Ribosome Entry Site) o Sitio Interno de entrada al Ribosoma es una secuencia nucleotídica que se encuentra en el extremo 5´UTR (untranslated region o región no traducida) que permite la iniciación de la síntesis proteica, la… …   Wikipedia Español

  • Hepatitis C virus internal ribosome entry site — Protein translation of most eukaryotic mRNAs requires association of Met tRNA, several eukaryotic initiation factors, and GTP with the 40S ribosomal subunit. The ribosome can only bind the capped mRNA after binding the initiator tRNA. Translation …   Wikipedia

  • EIF3A — Eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa, also known as EIF3S10, is a human gene.cite web | title = Entrez Gene: EIF3S10 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa| url =… …   Wikipedia

  • RPS6KB2 — Ribosomal protein S6 kinase, 70kDa, polypeptide 2, also known as RPS6KB2, is a human gene.cite web | title = Entrez Gene: RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

  • Facteurs d'initiation — Les facteurs d initiation ou facteurs de démarrage sont des protéines qui assistent le ribosome pour le démarrage de la traduction de l ARNm en protéines. Cette étape est cruciale, car c est elle qui permet à la machinerie cellulaire de… …   Wikipédia en Français

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”