SLC6A1

SLC6A1

Solute carrier family 6 (neurotransmitter transporter, GABA), member 1, also known as SLC6A1, is a human gene.cite web | title = Entrez Gene: SLC6A1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6529| accessdate = ]

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ee also

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* Solute carrier family

References

Further reading

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*cite journal | author=Nelson H, Mandiyan S, Nelson N |title=Cloning of the human brain GABA transporter. |journal=FEBS Lett. |volume=269 |issue= 1 |pages= 181–4 |year= 1990 |pmid= 2387399 |doi=
*cite journal | author=Huang F, Shi LJ, Heng HH, "et al." |title=Assignment of the human GABA transporter gene (GABATHG) locus to chromosome 3p24-p25. |journal=Genomics |volume=29 |issue= 1 |pages= 302–4 |year= 1996 |pmid= 8530094 |doi= 10.1006/geno.1995.1253
*cite journal | author=Bennett ER, Kanner BI |title=The membrane topology of GAT-1, a (Na+ + Cl-)-coupled gamma-aminobutyric acid transporter from rat brain. |journal=J. Biol. Chem. |volume=272 |issue= 2 |pages= 1203–10 |year= 1997 |pmid= 8995422 |doi=
*cite journal | author=Bismuth Y, Kavanaugh MP, Kanner BI |title=Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition. |journal=J. Biol. Chem. |volume=272 |issue= 26 |pages= 16096–102 |year= 1997 |pmid= 9195904 |doi=
*cite journal | author=DeFelipe J, González-Albo MC |title=Chandelier cell axons are immunoreactive for GAT-1 in the human neocortex. |journal=Neuroreport |volume=9 |issue= 3 |pages= 467–70 |year= 1998 |pmid= 9512391 |doi=
*cite journal | author=Conti F, Melone M, De Biasi S, "et al." |title=Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex. |journal=J. Comp. Neurol. |volume=396 |issue= 1 |pages= 51–63 |year= 1998 |pmid= 9623887 |doi=
*cite journal | author=Beckman ML, Bernstein EM, Quick MW |title=Protein kinase C regulates the interaction between a GABA transporter and syntaxin 1A. |journal=J. Neurosci. |volume=18 |issue= 16 |pages= 6103–12 |year= 1998 |pmid= 9698305 |doi=
*cite journal | author=Augood SJ, Waldvogel HJ, Münkle MC, "et al." |title=Localization of calcium-binding proteins and GABA transporter (GAT-1) messenger RNA in the human subthalamic nucleus. |journal=Neuroscience |volume=88 |issue= 2 |pages= 521–34 |year= 1999 |pmid= 10197772 |doi=
*cite journal | author=Ong WY, Yeo TT, Balcar VJ, Garey LJ |title=A light and electron microscopic study of GAT-1-positive cells in the cerebral cortex of man and monkey. |journal=J. Neurocytol. |volume=27 |issue= 10 |pages= 719–30 |year= 2000 |pmid= 10640187 |doi=
*cite journal | author=Deken SL, Beckman ML, Boos L, Quick MW |title=Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A. |journal=Nat. Neurosci. |volume=3 |issue= 10 |pages= 998–1003 |year= 2000 |pmid= 11017172 |doi= 10.1038/79939
*cite journal | author=Whitworth TL, Quick MW |title=Substrate-induced regulation of gamma-aminobutyric acid transporter trafficking requires tyrosine phosphorylation. |journal=J. Biol. Chem. |volume=276 |issue= 46 |pages= 42932–7 |year= 2001 |pmid= 11555659 |doi= 10.1074/jbc.M107638200
*cite journal | author=Hachiya Y, Takashima S |title=Development of GABAergic neurons and their transporter in human temporal cortex. |journal=Pediatr. Neurol. |volume=25 |issue= 5 |pages= 390–6 |year= 2002 |pmid= 11744314 |doi=
*cite journal | author=Quick MW |title=Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 8 |pages= 5686–91 |year= 2002 |pmid= 11960023 |doi= 10.1073/pnas.082712899
*cite journal | author=Kanner BI |title=Transmembrane domain I of the gamma-aminobutyric acid transporter GAT-1 plays a crucial role in the transition between cation leak and transport modes. |journal=J. Biol. Chem. |volume=278 |issue= 6 |pages= 3705–12 |year= 2003 |pmid= 12446715 |doi= 10.1074/jbc.M210525200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zomot E, Kanner BI |title=The interaction of the gamma-aminobutyric acid transporter GAT-1 with the neurotransmitter is selectively impaired by sulfhydryl modification of a conformationally sensitive cysteine residue engineered into extracellular loop IV. |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 42950–8 |year= 2003 |pmid= 12925537 |doi= 10.1074/jbc.M209307200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Zhou Y, Bennett ER, Kanner BI |title=The aqueous accessibility in the external half of transmembrane domain I of the GABA transporter GAT-1 Is modulated by its ligands. |journal=J. Biol. Chem. |volume=279 |issue= 14 |pages= 13800–8 |year= 2004 |pmid= 14744863 |doi= 10.1074/jbc.M311579200
*cite journal | author=Hu JH, Ma YH, Jiang J, "et al." |title=Cognitive impairment in mice over-expressing gamma-aminobutyric acid transporter 1 (GAT1). |journal=Neuroreport |volume=15 |issue= 1 |pages= 9–12 |year= 2004 |pmid= 15106822 |doi=
*cite journal | author=Korkhov VM, Farhan H, Freissmuth M, Sitte HH |title=Oligomerization of the {gamma}-aminobutyric acid transporter-1 is driven by an interplay of polar and hydrophobic interactions in transmembrane helix II. |journal=J. Biol. Chem. |volume=279 |issue= 53 |pages= 55728-36 |year= 2005 |pmid= 15496410 |doi= 10.1074/jbc.M409449200

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