FABP3

Fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor), also known as FABP3, is a human gene.cite web | title = Entrez Gene: FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2170| accessdate = ]

PBB_Summary
section_title =
summary_text = The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.cite web | title = Entrez Gene: FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2170| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Spener F, Unterberg C, Börchers T, Grosse R |title=Characteristics of fatty acid-binding proteins and their relation to mammary-derived growth inhibitor. |journal=Mol. Cell. Biochem. |volume=98 |issue= 1-2 |pages= 57–68 |year= 1991 |pmid= 2266970 |doi=
*cite journal | author=Zanotti G, Scapin G, Spadon P, "et al." |title=Three-dimensional structure of recombinant human muscle fatty acid-binding protein. |journal=J. Biol. Chem. |volume=267 |issue= 26 |pages= 18541–50 |year= 1992 |pmid= 1526991 |doi=
*cite journal | author=Peeters RA, Veerkamp JH, Geurts van Kessel A, "et al." |title=Cloning of the cDNA encoding human skeletal-muscle fatty-acid-binding protein, its peptide sequence and chromosomal localization. |journal=Biochem. J. |volume=276 ( Pt 1) |issue= |pages= 203–7 |year= 1991 |pmid= 1710107 |doi=
*cite journal | author=Tanaka T, Hirota Y, Sohmiya K, "et al." |title=Serum and urinary human heart fatty acid-binding protein in acute myocardial infarction. |journal=Clin. Biochem. |volume=24 |issue= 2 |pages= 195–201 |year= 1991 |pmid= 2040092 |doi=
*cite journal | author=Börchers T, Højrup P, Nielsen SU, "et al." |title=Revision of the amino acid sequence of human heart fatty acid-binding protein. |journal=Mol. Cell. Biochem. |volume=98 |issue= 1-2 |pages= 127–33 |year= 1991 |pmid= 2266954 |doi=
*cite journal | author=Offner GD, Brecher P, Sawlivich WB, "et al." |title=Characterization and amino acid sequence of a fatty acid-binding protein from human heart. |journal=Biochem. J. |volume=252 |issue= 1 |pages= 191–8 |year= 1988 |pmid= 3421901 |doi=
*cite journal | author=Kovalyov LI, Shishkin SS, Efimochkin AS, "et al." |title=The major protein expression profile and two-dimensional protein database of human heart. |journal=Electrophoresis |volume=16 |issue= 7 |pages= 1160–9 |year= 1996 |pmid= 7498159 |doi=
*cite journal | author=Nielsen SU, Spener F |title=Fatty acid-binding protein from rat heart is phosphorylated on Tyr19 in response to insulin stimulation. |journal=J. Lipid Res. |volume=34 |issue= 8 |pages= 1355–66 |year= 1993 |pmid= 7691977 |doi=
*cite journal | author=Huynh HT, Larsson C, Narod S, Pollak M |title=Tumor suppressor activity of the gene encoding mammary-derived growth inhibitor. |journal=Cancer Res. |volume=55 |issue= 11 |pages= 2225–31 |year= 1995 |pmid= 7757968 |doi=
*cite journal | author=Young AC, Scapin G, Kromminga A, "et al." |title=Structural studies on human muscle fatty acid binding protein at 1.4 A resolution: binding interactions with three C18 fatty acids. |journal=Structure |volume=2 |issue= 6 |pages= 523–34 |year= 1994 |pmid= 7922029 |doi=
*cite journal | author=Yang Y, Spitzer E, Kenney N, "et al." |title=Members of the fatty acid binding protein family are differentiation factors for the mammary gland. |journal=J. Cell Biol. |volume=127 |issue= 4 |pages= 1097–109 |year= 1994 |pmid= 7962070 |doi=
*cite journal | author=Troxler RF, Offner GD, Jiang JW, "et al." |title=Localization of the gene for human heart fatty acid binding protein to chromosome 1p32-1p33. |journal=Hum. Genet. |volume=92 |issue= 6 |pages= 563–6 |year= 1994 |pmid= 8262516 |doi=
*cite journal | author=Watanabe K, Wakabayashi H, Veerkamp JH, "et al." |title=Immunohistochemical distribution of heart-type fatty acid-binding protein immunoreactivity in normal human tissues and in acute myocardial infarct. |journal=J. Pathol. |volume=170 |issue= 1 |pages= 59–65 |year= 1993 |pmid= 8326460 |doi= 10.1002/path.1711700110
*cite journal | author=Phelan CM, Larsson C, Baird S, "et al." |title=The human mammary-derived growth inhibitor (MDGI) gene: genomic structure and mutation analysis in human breast tumors. |journal=Genomics |volume=34 |issue= 1 |pages= 63–8 |year= 1996 |pmid= 8661024 |doi= 10.1006/geno.1996.0241
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhao Y, Meng XM, Wei YJ, "et al." |title=Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I. |journal=J. Mol. Med. |volume=81 |issue= 5 |pages= 297–304 |year= 2004 |pmid= 12721663 |doi= 10.1007/s00109-003-0427-x
*cite journal | author=Cheon MS, Kim SH, Fountoulakis M, Lubec G |title=Heart type fatty acid binding protein (H-FABP) is decreased in brains of patients with Down syndrome and Alzheimer's disease. |journal=J. Neural Transm. Suppl. |volume= |issue= 67 |pages= 225–34 |year= 2004 |pmid= 15068254 |doi=
*cite journal | author=Hashimoto T, Kusakabe T, Sugino T, "et al." |title=Expression of heart-type fatty acid-binding protein in human gastric carcinoma and its association with tumor aggressiveness, metastasis and poor prognosis. |journal=Pathobiology |volume=71 |issue= 5 |pages= 267–73 |year= 2005 |pmid= 15459486 |doi= 10.1159/000080061
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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